Plasmodium co-infection protects against chikungunya virus-induced pathologies

Chikungunya virus (CHIKV) and Plasmodium co-infections have been reported in humans, but effects of the two pathogens on each other are unclear. Here, Teo et al. show in mice that Plasmodium infection affects CHIKV-specific T and B cell responses, leading to reduced joint inflammation.

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Detalles Bibliográficos
Autores principales:	Teck-Hui Teo, Fok-Moon Lum, Khairunnisa Ghaffar, Yi-Hao Chan, Siti Naqiah Amrun, Jeslin J. L. Tan, Cheryl Y. P. Lee, Tze-Kwang Chua, Guillaume Carissimo, Wendy W. L. Lee, Carla Claser, Ravisankar Rajarethinam, Laurent Rénia, Lisa F. P. Ng
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b8b01aeb3e824b2697f9b75b4b313838
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spelling	oai:doaj.org-article:b8b01aeb3e824b2697f9b75b4b3138382021-12-02T17:33:05ZPlasmodium co-infection protects against chikungunya virus-induced pathologies10.1038/s41467-018-06227-92041-1723https://doaj.org/article/b8b01aeb3e824b2697f9b75b4b3138382018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06227-9https://doaj.org/toc/2041-1723Chikungunya virus (CHIKV) and Plasmodium co-infections have been reported in humans, but effects of the two pathogens on each other are unclear. Here, Teo et al. show in mice that Plasmodium infection affects CHIKV-specific T and B cell responses, leading to reduced joint inflammation.Teck-Hui TeoFok-Moon LumKhairunnisa GhaffarYi-Hao ChanSiti Naqiah AmrunJeslin J. L. TanCheryl Y. P. LeeTze-Kwang ChuaGuillaume CarissimoWendy W. L. LeeCarla ClaserRavisankar RajarethinamLaurent RéniaLisa F. P. NgNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Teck-Hui Teo Fok-Moon Lum Khairunnisa Ghaffar Yi-Hao Chan Siti Naqiah Amrun Jeslin J. L. Tan Cheryl Y. P. Lee Tze-Kwang Chua Guillaume Carissimo Wendy W. L. Lee Carla Claser Ravisankar Rajarethinam Laurent Rénia Lisa F. P. Ng Plasmodium co-infection protects against chikungunya virus-induced pathologies
description	Chikungunya virus (CHIKV) and Plasmodium co-infections have been reported in humans, but effects of the two pathogens on each other are unclear. Here, Teo et al. show in mice that Plasmodium infection affects CHIKV-specific T and B cell responses, leading to reduced joint inflammation.
format	article
author	Teck-Hui Teo Fok-Moon Lum Khairunnisa Ghaffar Yi-Hao Chan Siti Naqiah Amrun Jeslin J. L. Tan Cheryl Y. P. Lee Tze-Kwang Chua Guillaume Carissimo Wendy W. L. Lee Carla Claser Ravisankar Rajarethinam Laurent Rénia Lisa F. P. Ng
author_facet	Teck-Hui Teo Fok-Moon Lum Khairunnisa Ghaffar Yi-Hao Chan Siti Naqiah Amrun Jeslin J. L. Tan Cheryl Y. P. Lee Tze-Kwang Chua Guillaume Carissimo Wendy W. L. Lee Carla Claser Ravisankar Rajarethinam Laurent Rénia Lisa F. P. Ng
author_sort	Teck-Hui Teo
title	Plasmodium co-infection protects against chikungunya virus-induced pathologies
title_short	Plasmodium co-infection protects against chikungunya virus-induced pathologies
title_full	Plasmodium co-infection protects against chikungunya virus-induced pathologies
title_fullStr	Plasmodium co-infection protects against chikungunya virus-induced pathologies
title_full_unstemmed	Plasmodium co-infection protects against chikungunya virus-induced pathologies
title_sort	plasmodium co-infection protects against chikungunya virus-induced pathologies
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/b8b01aeb3e824b2697f9b75b4b313838
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Plasmodium co-infection protects against chikungunya virus-induced pathologies

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