Cell competition corrects noisy Wnt morphogen gradients to achieve robust patterning in the zebrafish embryo
Gradients of morphogens such as Wnt provide instructive cues for cell identities during development. Here, the authors report that in the developing zebrafish embryo, cell competition and elimination of unfit cells are required for proper Wnt gradient formation.
Saved in:
Main Authors: | Yuki Akieda, Shohei Ogamino, Hironobu Furuie, Shizuka Ishitani, Ryutaro Akiyoshi, Jumpei Nogami, Takamasa Masuda, Nobuyuki Shimizu, Yasuyuki Ohkawa, Tohru Ishitani |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2019
|
Subjects: | |
Online Access: | https://doaj.org/article/b8bdf608e4c044408a0b01088889fa79 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
A phospho-switch controls RNF43-mediated degradation of Wnt receptors to suppress tumorigenesis
by: Tadasuke Tsukiyama, et al.
Published: (2020) -
Totipotency of mouse zygotes extends to single blastomeres of embryos at the four-cell stage
by: Marino Maemura, et al.
Published: (2021) -
Construction of a mammalian embryo model from stem cells organized by a morphogen signalling centre
by: Peng-Fei Xu, et al.
Published: (2021) -
Artificial morphogen-mediated differentiation in synthetic protocells
by: Liangfei Tian, et al.
Published: (2019) -
Visualisation and quantification of morphogen gradient formation in the zebrafish.
by: Steven A Harvey, et al.
Published: (2009)