Synthesis, Antimicrobial, Anticancer, PASS, Molecular Docking, Molecular Dynamic Simulations & Pharmacokinetic Predictions of Some Methyl β-D-Galactopyranoside Analogs

Synthesis, Antimicrobial, Anticancer, PASS, Molecular Docking, Molecular Dynamic Simulations & Pharmacokinetic Predictions of Some Methyl β-D-Galactopyranoside Analogs

A series of methyl β-D-galactopyranoside (MGP, <b>1</b>) analogs were selectively acylated with cinnamoyl chloride in anhydrous <i>N</i>,<i>N</i>-dimethylformamide/triethylamine to yield 6-<i>O</i>-substitution products, which was subsequently converte...

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Bibliographic Details
Main Authors: Md. Ruhul Amin, Farhana Yasmin, Mohammed Anowar Hosen, Sujan Dey, Shafi Mahmud, Md. Abu Saleh, Talha Bin Emran, Imtiaj Hasan, Yuki Fujii, Masao Yamada, Yasuhiro Ozeki, Sarkar Mohammad Abe Kawsar
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
methyl β-D-galactopyranoside
synthesis
PASS
molecular docking
molecular dynamics
Pharmacokinetic
Organic chemistry
QD241-441
Online Access:https://doaj.org/article/b8c474d5693f443ea778beb6a7bcf6a7
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https://doaj.org/article/b8c474d5693f443ea778beb6a7bcf6a7

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