Bisection of the X chromosome disrupts the initiation of chromosome silencing during meiosis in Caenorhabditis elegans

During meiosis, sex chromosomes show silenced gene expression that is disrupted when translocated to autosomes. Here, the authors engineer C. elegans with bisected X chromosomes and see active transcription in gonads, indicating continuity of sex chromosomes promotes silencing.

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Autores principales:	Yisrael Rappaport, Hanna Achache, Roni Falk, Omer Murik, Oren Ram, Yonatan B. Tzur
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b8c74cbf8faa449392cb3b9e02e9494e
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spelling	oai:doaj.org-article:b8c74cbf8faa449392cb3b9e02e9494e2021-12-02T16:27:56ZBisection of the X chromosome disrupts the initiation of chromosome silencing during meiosis in Caenorhabditis elegans10.1038/s41467-021-24815-02041-1723https://doaj.org/article/b8c74cbf8faa449392cb3b9e02e9494e2021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24815-0https://doaj.org/toc/2041-1723During meiosis, sex chromosomes show silenced gene expression that is disrupted when translocated to autosomes. Here, the authors engineer C. elegans with bisected X chromosomes and see active transcription in gonads, indicating continuity of sex chromosomes promotes silencing.Yisrael RappaportHanna AchacheRoni FalkOmer MurikOren RamYonatan B. TzurNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yisrael Rappaport Hanna Achache Roni Falk Omer Murik Oren Ram Yonatan B. Tzur Bisection of the X chromosome disrupts the initiation of chromosome silencing during meiosis in Caenorhabditis elegans
description	During meiosis, sex chromosomes show silenced gene expression that is disrupted when translocated to autosomes. Here, the authors engineer C. elegans with bisected X chromosomes and see active transcription in gonads, indicating continuity of sex chromosomes promotes silencing.
format	article
author	Yisrael Rappaport Hanna Achache Roni Falk Omer Murik Oren Ram Yonatan B. Tzur
author_facet	Yisrael Rappaport Hanna Achache Roni Falk Omer Murik Oren Ram Yonatan B. Tzur
author_sort	Yisrael Rappaport
title	Bisection of the X chromosome disrupts the initiation of chromosome silencing during meiosis in Caenorhabditis elegans
title_short	Bisection of the X chromosome disrupts the initiation of chromosome silencing during meiosis in Caenorhabditis elegans
title_full	Bisection of the X chromosome disrupts the initiation of chromosome silencing during meiosis in Caenorhabditis elegans
title_fullStr	Bisection of the X chromosome disrupts the initiation of chromosome silencing during meiosis in Caenorhabditis elegans
title_full_unstemmed	Bisection of the X chromosome disrupts the initiation of chromosome silencing during meiosis in Caenorhabditis elegans
title_sort	bisection of the x chromosome disrupts the initiation of chromosome silencing during meiosis in caenorhabditis elegans
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/b8c74cbf8faa449392cb3b9e02e9494e
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Bisection of the X chromosome disrupts the initiation of chromosome silencing during meiosis in Caenorhabditis elegans

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