Bisection of the X chromosome disrupts the initiation of chromosome silencing during meiosis in Caenorhabditis elegans

During meiosis, sex chromosomes show silenced gene expression that is disrupted when translocated to autosomes. Here, the authors engineer C. elegans with bisected X chromosomes and see active transcription in gonads, indicating continuity of sex chromosomes promotes silencing.

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Auteurs principaux: Yisrael Rappaport, Hanna Achache, Roni Falk, Omer Murik, Oren Ram, Yonatan B. Tzur
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/b8c74cbf8faa449392cb3b9e02e9494e
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