Critical appraisal of ophthalmic ketorolac in treatment of pain and inflammation following cataract surgery

Critical appraisal of ophthalmic ketorolac in treatment of pain and inflammation following cataract surgery

Rahul Reddy, Stephen Jae KimDepartment of Ophthalmology, Vanderbilt University, Nashville, TN, USABackground: The purpose of this review was to provide a critical appraisal of the literature supporting the efficacy of ophthalmic ketorolac (Acuvail®) in the treatment of pain and inflammat...

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Autores principales: Reddy RK, Kim SJ
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2011
Materias:
Ophthalmology
RE1-994
Acceso en línea:https://doaj.org/article/b8c7d4d96542419f96368a3dd2c953fd
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spelling oai:doaj.org-article:b8c7d4d96542419f96368a3dd2c953fd2021-12-02T06:15:45ZCritical appraisal of ophthalmic ketorolac in treatment of pain and inflammation following cataract surgery1177-54671177-5483https://doaj.org/article/b8c7d4d96542419f96368a3dd2c953fd2011-06-01T00:00:00Zhttp://www.dovepress.com/critical-appraisal-of-ophthalmic-ketorolac-in-treatment-of-pain-and-in-a7593https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Rahul Reddy, Stephen Jae KimDepartment of Ophthalmology, Vanderbilt University, Nashville, TN, USABackground: The purpose of this review was to provide a critical appraisal of the literature supporting the efficacy of ophthalmic ketorolac (Acuvail®) in the treatment of pain and inflammation after cataract surgery.Methods: Literature search and expert opinion of the authors.Results: Recent studies indicate greater intraocular drug levels in the anterior chamber and iris-ciliary body after topical application of Acuvail in comparison with older formulations of ketorolac. A large randomized, multicenter, placebo-controlled study demonstrated significantly less inflammation and pain after cataract surgery using Acuvail.Conclusion: Acuvail appears to be effective in reducing post-cataract surgery pain and inflammation.Keywords: ketorolac tromethamine, Acuvail®, postsurgical, cystoid macular edema, nonsteroidal anti-inflammatory drugsReddy RKKim SJDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2011, Iss default, Pp 751-758 (2011)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Reddy RK
Kim SJ
Critical appraisal of ophthalmic ketorolac in treatment of pain and inflammation following cataract surgery
description Rahul Reddy, Stephen Jae KimDepartment of Ophthalmology, Vanderbilt University, Nashville, TN, USABackground: The purpose of this review was to provide a critical appraisal of the literature supporting the efficacy of ophthalmic ketorolac (Acuvail®) in the treatment of pain and inflammation after cataract surgery.Methods: Literature search and expert opinion of the authors.Results: Recent studies indicate greater intraocular drug levels in the anterior chamber and iris-ciliary body after topical application of Acuvail in comparison with older formulations of ketorolac. A large randomized, multicenter, placebo-controlled study demonstrated significantly less inflammation and pain after cataract surgery using Acuvail.Conclusion: Acuvail appears to be effective in reducing post-cataract surgery pain and inflammation.Keywords: ketorolac tromethamine, Acuvail®, postsurgical, cystoid macular edema, nonsteroidal anti-inflammatory drugs
format article
author Reddy RK
Kim SJ
author_facet Reddy RK
Kim SJ
author_sort Reddy RK
title Critical appraisal of ophthalmic ketorolac in treatment of pain and inflammation following cataract surgery
title_short Critical appraisal of ophthalmic ketorolac in treatment of pain and inflammation following cataract surgery
title_full Critical appraisal of ophthalmic ketorolac in treatment of pain and inflammation following cataract surgery
title_fullStr Critical appraisal of ophthalmic ketorolac in treatment of pain and inflammation following cataract surgery
title_full_unstemmed Critical appraisal of ophthalmic ketorolac in treatment of pain and inflammation following cataract surgery
title_sort critical appraisal of ophthalmic ketorolac in treatment of pain and inflammation following cataract surgery
publisher Dove Medical Press
publishDate 2011
url https://doaj.org/article/b8c7d4d96542419f96368a3dd2c953fd
work_keys_str_mv AT reddyrk criticalappraisalofophthalmicketorolacintreatmentofpainandinflammationfollowingcataractsurgery
AT kimsj criticalappraisalofophthalmicketorolacintreatmentofpainandinflammationfollowingcataractsurgery
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