Multiple genetic alterations within the PI3K pathway are responsible for AKT activation in patients with ovarian carcinoma.

Multiple genetic alterations within the PI3K pathway are responsible for AKT activation in patients with ovarian carcinoma.

The phosphatidylinositol 3-kinase (PI3K)/AKT pathway is activated in multiple cancers including ovarian carcinoma (OC). However, the relative contribution of the single components within the PI3K pathway to AKT activation in OC is still unclear. We examined 98 tumor samples from Italian OC patients...

Full description

Saved in:
Bibliographic Details
Main Authors: Carmela De Marco, Nicola Rinaldo, Paola Bruni, Carmine Malzoni, Fulvio Zullo, Fernanda Fabiani, Simona Losito, Marianna Scrima, Federica Zito Marino, Renato Franco, Alfina Quintiero, Valter Agosti, Giuseppe Viglietto
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/b8cea4f6b7944fc39c67c5c7718c6df6
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items