A Review on Biphasic Calcium Phosphate Materials Derived from Fish Discards

This review summarizes the results reported on the production of biphasic calcium phosphate (BCP) materials derived from fish wastes (i.e., heads, bones, skins, and viscera), known as fish discards, and offers an in-depth discussion on their promising potential for various applications in many field...

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Autores principales:	Liviu Duta, Gabriela Dorcioman, Valentina Grumezescu
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	biphasic calcium phosphates fish discards bone-tissue engineering Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/b8cff74eefa049d89838472e421f0455
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spelling	oai:doaj.org-article:b8cff74eefa049d89838472e421f04552021-11-25T18:30:24ZA Review on Biphasic Calcium Phosphate Materials Derived from Fish Discards10.3390/nano111128562079-4991https://doaj.org/article/b8cff74eefa049d89838472e421f04552021-10-01T00:00:00Zhttps://www.mdpi.com/2079-4991/11/11/2856https://doaj.org/toc/2079-4991This review summarizes the results reported on the production of biphasic calcium phosphate (BCP) materials derived from fish wastes (i.e., heads, bones, skins, and viscera), known as fish discards, and offers an in-depth discussion on their promising potential for various applications in many fields, especially the biomedical one. Thus, considerable scientific and technological efforts were recently focused on the capability of these sustainable materials to be transformed into economically attractive and highly valuable by-products. As a consequence of using these wastes, plenty of beneficial social effects, with both economic and environmental impact, will arise. In the biomedical field, there is a strong and continuous interest for the development of innovative solutions for healthcare improvement using alternative materials of biogenic origin. Thus, the orthopedic field has witnessed a significant development due to an increased demand for a large variety of implants, grafts, and/or scaffolds. This is mainly due to the increase of life expectancy and higher frequency of bone-associated injuries and diseases. As a consequence, the domain of bone-tissue engineering has expanded to be able to address a plethora of bone-related traumas and to deliver a viable and efficient substitute to allografts or autografts by combining bioactive materials and cells for bone-tissue ingrowth. Among biomaterials, calcium phosphate (CaP)-based bio-ceramics are widely used in medicine, in particular in orthopedics and dentistry, due to their excellent bioactive, osteoconductive, and osteointegrative characteristics. Recently, BCP materials (synthetic or natural), a class of CaP, which consist of a mixture of two phases, hydroxyapatite (HA) and beta tricalcium phosphate (β-TCP), in different concentrations, gained increased attention due to their superior overall performances as compared to single-phase formulations. Moreover, the exploitation of BCP materials from by-products of fish industry was reported to be a safe, cheap, and simple procedure. In the dedicated literature, there are many reviews on synthetic HA, β-TCP, or BCP materials, but to the best of our knowledge, this is the first collection of results on the effects of processing conditions on the morphological, compositional, structural, mechanical, and biological properties of the fish discard-derived BCPs along with the tailoring of their features for various applications.Liviu DutaGabriela DorciomanValentina GrumezescuMDPI AGarticlebiphasic calcium phosphatesfish discardsbone-tissue engineeringChemistryQD1-999ENNanomaterials, Vol 11, Iss 2856, p 2856 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	biphasic calcium phosphates fish discards bone-tissue engineering Chemistry QD1-999
spellingShingle	biphasic calcium phosphates fish discards bone-tissue engineering Chemistry QD1-999 Liviu Duta Gabriela Dorcioman Valentina Grumezescu A Review on Biphasic Calcium Phosphate Materials Derived from Fish Discards
description	This review summarizes the results reported on the production of biphasic calcium phosphate (BCP) materials derived from fish wastes (i.e., heads, bones, skins, and viscera), known as fish discards, and offers an in-depth discussion on their promising potential for various applications in many fields, especially the biomedical one. Thus, considerable scientific and technological efforts were recently focused on the capability of these sustainable materials to be transformed into economically attractive and highly valuable by-products. As a consequence of using these wastes, plenty of beneficial social effects, with both economic and environmental impact, will arise. In the biomedical field, there is a strong and continuous interest for the development of innovative solutions for healthcare improvement using alternative materials of biogenic origin. Thus, the orthopedic field has witnessed a significant development due to an increased demand for a large variety of implants, grafts, and/or scaffolds. This is mainly due to the increase of life expectancy and higher frequency of bone-associated injuries and diseases. As a consequence, the domain of bone-tissue engineering has expanded to be able to address a plethora of bone-related traumas and to deliver a viable and efficient substitute to allografts or autografts by combining bioactive materials and cells for bone-tissue ingrowth. Among biomaterials, calcium phosphate (CaP)-based bio-ceramics are widely used in medicine, in particular in orthopedics and dentistry, due to their excellent bioactive, osteoconductive, and osteointegrative characteristics. Recently, BCP materials (synthetic or natural), a class of CaP, which consist of a mixture of two phases, hydroxyapatite (HA) and beta tricalcium phosphate (β-TCP), in different concentrations, gained increased attention due to their superior overall performances as compared to single-phase formulations. Moreover, the exploitation of BCP materials from by-products of fish industry was reported to be a safe, cheap, and simple procedure. In the dedicated literature, there are many reviews on synthetic HA, β-TCP, or BCP materials, but to the best of our knowledge, this is the first collection of results on the effects of processing conditions on the morphological, compositional, structural, mechanical, and biological properties of the fish discard-derived BCPs along with the tailoring of their features for various applications.
format	article
author	Liviu Duta Gabriela Dorcioman Valentina Grumezescu
author_facet	Liviu Duta Gabriela Dorcioman Valentina Grumezescu
author_sort	Liviu Duta
title	A Review on Biphasic Calcium Phosphate Materials Derived from Fish Discards
title_short	A Review on Biphasic Calcium Phosphate Materials Derived from Fish Discards
title_full	A Review on Biphasic Calcium Phosphate Materials Derived from Fish Discards
title_fullStr	A Review on Biphasic Calcium Phosphate Materials Derived from Fish Discards
title_full_unstemmed	A Review on Biphasic Calcium Phosphate Materials Derived from Fish Discards
title_sort	review on biphasic calcium phosphate materials derived from fish discards
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/b8cff74eefa049d89838472e421f0455
work_keys_str_mv	AT liviuduta areviewonbiphasiccalciumphosphatematerialsderivedfromfishdiscards AT gabrieladorcioman areviewonbiphasiccalciumphosphatematerialsderivedfromfishdiscards AT valentinagrumezescu areviewonbiphasiccalciumphosphatematerialsderivedfromfishdiscards AT liviuduta reviewonbiphasiccalciumphosphatematerialsderivedfromfishdiscards AT gabrieladorcioman reviewonbiphasiccalciumphosphatematerialsderivedfromfishdiscards AT valentinagrumezescu reviewonbiphasiccalciumphosphatematerialsderivedfromfishdiscards
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A Review on Biphasic Calcium Phosphate Materials Derived from Fish Discards

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