Dual regulation of Arabidopsis AGO2 by arginine methylation
AGO2 is a core component of the RNAi machinery and contributes to plant immunity during bacterial infection. Here the authors show that AGO2 activity is suppressed by arginine methylation which not only promotes AGO2 degradation but also recruits TSN proteins to degrade AGO2-associated small RNAs.
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Nature Portfolio
2019
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oai:doaj.org-article:b8d3c80b350e4fce9685f67c9f82325f2021-12-02T17:02:15ZDual regulation of Arabidopsis AGO2 by arginine methylation10.1038/s41467-019-08787-w2041-1723https://doaj.org/article/b8d3c80b350e4fce9685f67c9f82325f2019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08787-whttps://doaj.org/toc/2041-1723AGO2 is a core component of the RNAi machinery and contributes to plant immunity during bacterial infection. Here the authors show that AGO2 activity is suppressed by arginine methylation which not only promotes AGO2 degradation but also recruits TSN proteins to degrade AGO2-associated small RNAs.Po HuHongwei ZhaoPei ZhuYongsheng XiaoWeili MiaoYinsheng WangHailing JinNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019) |
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Science Q Po Hu Hongwei Zhao Pei Zhu Yongsheng Xiao Weili Miao Yinsheng Wang Hailing Jin Dual regulation of Arabidopsis AGO2 by arginine methylation |
description |
AGO2 is a core component of the RNAi machinery and contributes to plant immunity during bacterial infection. Here the authors show that AGO2 activity is suppressed by arginine methylation which not only promotes AGO2 degradation but also recruits TSN proteins to degrade AGO2-associated small RNAs. |
format |
article |
author |
Po Hu Hongwei Zhao Pei Zhu Yongsheng Xiao Weili Miao Yinsheng Wang Hailing Jin |
author_facet |
Po Hu Hongwei Zhao Pei Zhu Yongsheng Xiao Weili Miao Yinsheng Wang Hailing Jin |
author_sort |
Po Hu |
title |
Dual regulation of Arabidopsis AGO2 by arginine methylation |
title_short |
Dual regulation of Arabidopsis AGO2 by arginine methylation |
title_full |
Dual regulation of Arabidopsis AGO2 by arginine methylation |
title_fullStr |
Dual regulation of Arabidopsis AGO2 by arginine methylation |
title_full_unstemmed |
Dual regulation of Arabidopsis AGO2 by arginine methylation |
title_sort |
dual regulation of arabidopsis ago2 by arginine methylation |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/b8d3c80b350e4fce9685f67c9f82325f |
work_keys_str_mv |
AT pohu dualregulationofarabidopsisago2byargininemethylation AT hongweizhao dualregulationofarabidopsisago2byargininemethylation AT peizhu dualregulationofarabidopsisago2byargininemethylation AT yongshengxiao dualregulationofarabidopsisago2byargininemethylation AT weilimiao dualregulationofarabidopsisago2byargininemethylation AT yinshengwang dualregulationofarabidopsisago2byargininemethylation AT hailingjin dualregulationofarabidopsisago2byargininemethylation |
_version_ |
1718381929485565952 |