Dual regulation of Arabidopsis AGO2 by arginine methylation

AGO2 is a core component of the RNAi machinery and contributes to plant immunity during bacterial infection. Here the authors show that AGO2 activity is suppressed by arginine methylation which not only promotes AGO2 degradation but also recruits TSN proteins to degrade AGO2-associated small RNAs.

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Auteurs principaux:	Po Hu, Hongwei Zhao, Pei Zhu, Yongsheng Xiao, Weili Miao, Yinsheng Wang, Hailing Jin
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2019
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/b8d3c80b350e4fce9685f67c9f82325f
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spelling	oai:doaj.org-article:b8d3c80b350e4fce9685f67c9f82325f2021-12-02T17:02:15ZDual regulation of Arabidopsis AGO2 by arginine methylation10.1038/s41467-019-08787-w2041-1723https://doaj.org/article/b8d3c80b350e4fce9685f67c9f82325f2019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08787-whttps://doaj.org/toc/2041-1723AGO2 is a core component of the RNAi machinery and contributes to plant immunity during bacterial infection. Here the authors show that AGO2 activity is suppressed by arginine methylation which not only promotes AGO2 degradation but also recruits TSN proteins to degrade AGO2-associated small RNAs.Po HuHongwei ZhaoPei ZhuYongsheng XiaoWeili MiaoYinsheng WangHailing JinNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Po Hu Hongwei Zhao Pei Zhu Yongsheng Xiao Weili Miao Yinsheng Wang Hailing Jin Dual regulation of Arabidopsis AGO2 by arginine methylation
description	AGO2 is a core component of the RNAi machinery and contributes to plant immunity during bacterial infection. Here the authors show that AGO2 activity is suppressed by arginine methylation which not only promotes AGO2 degradation but also recruits TSN proteins to degrade AGO2-associated small RNAs.
format	article
author	Po Hu Hongwei Zhao Pei Zhu Yongsheng Xiao Weili Miao Yinsheng Wang Hailing Jin
author_facet	Po Hu Hongwei Zhao Pei Zhu Yongsheng Xiao Weili Miao Yinsheng Wang Hailing Jin
author_sort	Po Hu
title	Dual regulation of Arabidopsis AGO2 by arginine methylation
title_short	Dual regulation of Arabidopsis AGO2 by arginine methylation
title_full	Dual regulation of Arabidopsis AGO2 by arginine methylation
title_fullStr	Dual regulation of Arabidopsis AGO2 by arginine methylation
title_full_unstemmed	Dual regulation of Arabidopsis AGO2 by arginine methylation
title_sort	dual regulation of arabidopsis ago2 by arginine methylation
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/b8d3c80b350e4fce9685f67c9f82325f
work_keys_str_mv	AT pohu dualregulationofarabidopsisago2byargininemethylation AT hongweizhao dualregulationofarabidopsisago2byargininemethylation AT peizhu dualregulationofarabidopsisago2byargininemethylation AT yongshengxiao dualregulationofarabidopsisago2byargininemethylation AT weilimiao dualregulationofarabidopsisago2byargininemethylation AT yinshengwang dualregulationofarabidopsisago2byargininemethylation AT hailingjin dualregulationofarabidopsisago2byargininemethylation
_version_	1718381929485565952

Dual regulation of Arabidopsis AGO2 by arginine methylation

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