Dual regulation of Arabidopsis AGO2 by arginine methylation

AGO2 is a core component of the RNAi machinery and contributes to plant immunity during bacterial infection. Here the authors show that AGO2 activity is suppressed by arginine methylation which not only promotes AGO2 degradation but also recruits TSN proteins to degrade AGO2-associated small RNAs.

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Autores principales: Po Hu, Hongwei Zhao, Pei Zhu, Yongsheng Xiao, Weili Miao, Yinsheng Wang, Hailing Jin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/b8d3c80b350e4fce9685f67c9f82325f
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spelling oai:doaj.org-article:b8d3c80b350e4fce9685f67c9f82325f2021-12-02T17:02:15ZDual regulation of Arabidopsis AGO2 by arginine methylation10.1038/s41467-019-08787-w2041-1723https://doaj.org/article/b8d3c80b350e4fce9685f67c9f82325f2019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08787-whttps://doaj.org/toc/2041-1723AGO2 is a core component of the RNAi machinery and contributes to plant immunity during bacterial infection. Here the authors show that AGO2 activity is suppressed by arginine methylation which not only promotes AGO2 degradation but also recruits TSN proteins to degrade AGO2-associated small RNAs.Po HuHongwei ZhaoPei ZhuYongsheng XiaoWeili MiaoYinsheng WangHailing JinNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Po Hu
Hongwei Zhao
Pei Zhu
Yongsheng Xiao
Weili Miao
Yinsheng Wang
Hailing Jin
Dual regulation of Arabidopsis AGO2 by arginine methylation
description AGO2 is a core component of the RNAi machinery and contributes to plant immunity during bacterial infection. Here the authors show that AGO2 activity is suppressed by arginine methylation which not only promotes AGO2 degradation but also recruits TSN proteins to degrade AGO2-associated small RNAs.
format article
author Po Hu
Hongwei Zhao
Pei Zhu
Yongsheng Xiao
Weili Miao
Yinsheng Wang
Hailing Jin
author_facet Po Hu
Hongwei Zhao
Pei Zhu
Yongsheng Xiao
Weili Miao
Yinsheng Wang
Hailing Jin
author_sort Po Hu
title Dual regulation of Arabidopsis AGO2 by arginine methylation
title_short Dual regulation of Arabidopsis AGO2 by arginine methylation
title_full Dual regulation of Arabidopsis AGO2 by arginine methylation
title_fullStr Dual regulation of Arabidopsis AGO2 by arginine methylation
title_full_unstemmed Dual regulation of Arabidopsis AGO2 by arginine methylation
title_sort dual regulation of arabidopsis ago2 by arginine methylation
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/b8d3c80b350e4fce9685f67c9f82325f
work_keys_str_mv AT pohu dualregulationofarabidopsisago2byargininemethylation
AT hongweizhao dualregulationofarabidopsisago2byargininemethylation
AT peizhu dualregulationofarabidopsisago2byargininemethylation
AT yongshengxiao dualregulationofarabidopsisago2byargininemethylation
AT weilimiao dualregulationofarabidopsisago2byargininemethylation
AT yinshengwang dualregulationofarabidopsisago2byargininemethylation
AT hailingjin dualregulationofarabidopsisago2byargininemethylation
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