Interpreting molecular similarity between patients as a determinant of disease comorbidity relationships

Disease comorbidity is attracting increasing attention, but the involvement of molecular factors in forecasting risk of a disease in the presence of other diseases is poorly understood. Here the authors build a disease interaction network based on gene expression profile and discover new comorbidity...

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Autores principales:	Jon Sánchez-Valle, Héctor Tejero, José María Fernández, David Juan, Beatriz Urda-García, Salvador Capella-Gutiérrez, Fátima Al-Shahrour, Rafael Tabarés-Seisdedos, Anaïs Baudot, Vera Pancaldi, Alfonso Valencia
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b8e750206f194b8fa013e289241caa12
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spelling	oai:doaj.org-article:b8e750206f194b8fa013e289241caa122021-12-02T15:03:03ZInterpreting molecular similarity between patients as a determinant of disease comorbidity relationships10.1038/s41467-020-16540-x2041-1723https://doaj.org/article/b8e750206f194b8fa013e289241caa122020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16540-xhttps://doaj.org/toc/2041-1723Disease comorbidity is attracting increasing attention, but the involvement of molecular factors in forecasting risk of a disease in the presence of other diseases is poorly understood. Here the authors build a disease interaction network based on gene expression profile and discover new comorbidity relationships in patient subgroups.Jon Sánchez-ValleHéctor TejeroJosé María FernándezDavid JuanBeatriz Urda-GarcíaSalvador Capella-GutiérrezFátima Al-ShahrourRafael Tabarés-SeisdedosAnaïs BaudotVera PancaldiAlfonso ValenciaNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jon Sánchez-Valle Héctor Tejero José María Fernández David Juan Beatriz Urda-García Salvador Capella-Gutiérrez Fátima Al-Shahrour Rafael Tabarés-Seisdedos Anaïs Baudot Vera Pancaldi Alfonso Valencia Interpreting molecular similarity between patients as a determinant of disease comorbidity relationships
description	Disease comorbidity is attracting increasing attention, but the involvement of molecular factors in forecasting risk of a disease in the presence of other diseases is poorly understood. Here the authors build a disease interaction network based on gene expression profile and discover new comorbidity relationships in patient subgroups.
format	article
author	Jon Sánchez-Valle Héctor Tejero José María Fernández David Juan Beatriz Urda-García Salvador Capella-Gutiérrez Fátima Al-Shahrour Rafael Tabarés-Seisdedos Anaïs Baudot Vera Pancaldi Alfonso Valencia
author_facet	Jon Sánchez-Valle Héctor Tejero José María Fernández David Juan Beatriz Urda-García Salvador Capella-Gutiérrez Fátima Al-Shahrour Rafael Tabarés-Seisdedos Anaïs Baudot Vera Pancaldi Alfonso Valencia
author_sort	Jon Sánchez-Valle
title	Interpreting molecular similarity between patients as a determinant of disease comorbidity relationships
title_short	Interpreting molecular similarity between patients as a determinant of disease comorbidity relationships
title_full	Interpreting molecular similarity between patients as a determinant of disease comorbidity relationships
title_fullStr	Interpreting molecular similarity between patients as a determinant of disease comorbidity relationships
title_full_unstemmed	Interpreting molecular similarity between patients as a determinant of disease comorbidity relationships
title_sort	interpreting molecular similarity between patients as a determinant of disease comorbidity relationships
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/b8e750206f194b8fa013e289241caa12
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Interpreting molecular similarity between patients as a determinant of disease comorbidity relationships

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