MOCCASIN: a method for correcting for known and unknown confounders in RNA splicing analysis

Confounding factors on gene expression analysis can be analyzed by several existing tools. Here the authors develop an algorithm called MOCCASIN to correct the effect of known and unknown confounders on RNA splicing quantification.

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Autores principales: Barry Slaff, Caleb M. Radens, Paul Jewell, Anupama Jha, Nicholas F. Lahens, Gregory R. Grant, Andrei Thomas-Tikhonenko, Kristen W. Lynch, Yoseph Barash
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/b8ed04d2aafd4e4a8c327a67fed001a0
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spelling oai:doaj.org-article:b8ed04d2aafd4e4a8c327a67fed001a02021-12-02T18:06:34ZMOCCASIN: a method for correcting for known and unknown confounders in RNA splicing analysis10.1038/s41467-021-23608-92041-1723https://doaj.org/article/b8ed04d2aafd4e4a8c327a67fed001a02021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23608-9https://doaj.org/toc/2041-1723Confounding factors on gene expression analysis can be analyzed by several existing tools. Here the authors develop an algorithm called MOCCASIN to correct the effect of known and unknown confounders on RNA splicing quantification.Barry SlaffCaleb M. RadensPaul JewellAnupama JhaNicholas F. LahensGregory R. GrantAndrei Thomas-TikhonenkoKristen W. LynchYoseph BarashNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Barry Slaff
Caleb M. Radens
Paul Jewell
Anupama Jha
Nicholas F. Lahens
Gregory R. Grant
Andrei Thomas-Tikhonenko
Kristen W. Lynch
Yoseph Barash
MOCCASIN: a method for correcting for known and unknown confounders in RNA splicing analysis
description Confounding factors on gene expression analysis can be analyzed by several existing tools. Here the authors develop an algorithm called MOCCASIN to correct the effect of known and unknown confounders on RNA splicing quantification.
format article
author Barry Slaff
Caleb M. Radens
Paul Jewell
Anupama Jha
Nicholas F. Lahens
Gregory R. Grant
Andrei Thomas-Tikhonenko
Kristen W. Lynch
Yoseph Barash
author_facet Barry Slaff
Caleb M. Radens
Paul Jewell
Anupama Jha
Nicholas F. Lahens
Gregory R. Grant
Andrei Thomas-Tikhonenko
Kristen W. Lynch
Yoseph Barash
author_sort Barry Slaff
title MOCCASIN: a method for correcting for known and unknown confounders in RNA splicing analysis
title_short MOCCASIN: a method for correcting for known and unknown confounders in RNA splicing analysis
title_full MOCCASIN: a method for correcting for known and unknown confounders in RNA splicing analysis
title_fullStr MOCCASIN: a method for correcting for known and unknown confounders in RNA splicing analysis
title_full_unstemmed MOCCASIN: a method for correcting for known and unknown confounders in RNA splicing analysis
title_sort moccasin: a method for correcting for known and unknown confounders in rna splicing analysis
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/b8ed04d2aafd4e4a8c327a67fed001a0
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