MOCCASIN: a method for correcting for known and unknown confounders in RNA splicing analysis
Confounding factors on gene expression analysis can be analyzed by several existing tools. Here the authors develop an algorithm called MOCCASIN to correct the effect of known and unknown confounders on RNA splicing quantification.
Guardado en:
Autores principales: | , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/b8ed04d2aafd4e4a8c327a67fed001a0 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:b8ed04d2aafd4e4a8c327a67fed001a0 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:b8ed04d2aafd4e4a8c327a67fed001a02021-12-02T18:06:34ZMOCCASIN: a method for correcting for known and unknown confounders in RNA splicing analysis10.1038/s41467-021-23608-92041-1723https://doaj.org/article/b8ed04d2aafd4e4a8c327a67fed001a02021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23608-9https://doaj.org/toc/2041-1723Confounding factors on gene expression analysis can be analyzed by several existing tools. Here the authors develop an algorithm called MOCCASIN to correct the effect of known and unknown confounders on RNA splicing quantification.Barry SlaffCaleb M. RadensPaul JewellAnupama JhaNicholas F. LahensGregory R. GrantAndrei Thomas-TikhonenkoKristen W. LynchYoseph BarashNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Barry Slaff Caleb M. Radens Paul Jewell Anupama Jha Nicholas F. Lahens Gregory R. Grant Andrei Thomas-Tikhonenko Kristen W. Lynch Yoseph Barash MOCCASIN: a method for correcting for known and unknown confounders in RNA splicing analysis |
description |
Confounding factors on gene expression analysis can be analyzed by several existing tools. Here the authors develop an algorithm called MOCCASIN to correct the effect of known and unknown confounders on RNA splicing quantification. |
format |
article |
author |
Barry Slaff Caleb M. Radens Paul Jewell Anupama Jha Nicholas F. Lahens Gregory R. Grant Andrei Thomas-Tikhonenko Kristen W. Lynch Yoseph Barash |
author_facet |
Barry Slaff Caleb M. Radens Paul Jewell Anupama Jha Nicholas F. Lahens Gregory R. Grant Andrei Thomas-Tikhonenko Kristen W. Lynch Yoseph Barash |
author_sort |
Barry Slaff |
title |
MOCCASIN: a method for correcting for known and unknown confounders in RNA splicing analysis |
title_short |
MOCCASIN: a method for correcting for known and unknown confounders in RNA splicing analysis |
title_full |
MOCCASIN: a method for correcting for known and unknown confounders in RNA splicing analysis |
title_fullStr |
MOCCASIN: a method for correcting for known and unknown confounders in RNA splicing analysis |
title_full_unstemmed |
MOCCASIN: a method for correcting for known and unknown confounders in RNA splicing analysis |
title_sort |
moccasin: a method for correcting for known and unknown confounders in rna splicing analysis |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/b8ed04d2aafd4e4a8c327a67fed001a0 |
work_keys_str_mv |
AT barryslaff moccasinamethodforcorrectingforknownandunknownconfoundersinrnasplicinganalysis AT calebmradens moccasinamethodforcorrectingforknownandunknownconfoundersinrnasplicinganalysis AT pauljewell moccasinamethodforcorrectingforknownandunknownconfoundersinrnasplicinganalysis AT anupamajha moccasinamethodforcorrectingforknownandunknownconfoundersinrnasplicinganalysis AT nicholasflahens moccasinamethodforcorrectingforknownandunknownconfoundersinrnasplicinganalysis AT gregoryrgrant moccasinamethodforcorrectingforknownandunknownconfoundersinrnasplicinganalysis AT andreithomastikhonenko moccasinamethodforcorrectingforknownandunknownconfoundersinrnasplicinganalysis AT kristenwlynch moccasinamethodforcorrectingforknownandunknownconfoundersinrnasplicinganalysis AT yosephbarash moccasinamethodforcorrectingforknownandunknownconfoundersinrnasplicinganalysis |
_version_ |
1718378652286058496 |