MOCCASIN: a method for correcting for known and unknown confounders in RNA splicing analysis

Confounding factors on gene expression analysis can be analyzed by several existing tools. Here the authors develop an algorithm called MOCCASIN to correct the effect of known and unknown confounders on RNA splicing quantification.

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Bibliographic Details
Main Authors:	Barry Slaff, Caleb M. Radens, Paul Jewell, Anupama Jha, Nicholas F. Lahens, Gregory R. Grant, Andrei Thomas-Tikhonenko, Kristen W. Lynch, Yoseph Barash
Format:	article
Language:	EN
Published:	Nature Portfolio 2021
Subjects:	Science Q
Online Access:	https://doaj.org/article/b8ed04d2aafd4e4a8c327a67fed001a0
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spelling	oai:doaj.org-article:b8ed04d2aafd4e4a8c327a67fed001a02021-12-02T18:06:34ZMOCCASIN: a method for correcting for known and unknown confounders in RNA splicing analysis10.1038/s41467-021-23608-92041-1723https://doaj.org/article/b8ed04d2aafd4e4a8c327a67fed001a02021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23608-9https://doaj.org/toc/2041-1723Confounding factors on gene expression analysis can be analyzed by several existing tools. Here the authors develop an algorithm called MOCCASIN to correct the effect of known and unknown confounders on RNA splicing quantification.Barry SlaffCaleb M. RadensPaul JewellAnupama JhaNicholas F. LahensGregory R. GrantAndrei Thomas-TikhonenkoKristen W. LynchYoseph BarashNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Barry Slaff Caleb M. Radens Paul Jewell Anupama Jha Nicholas F. Lahens Gregory R. Grant Andrei Thomas-Tikhonenko Kristen W. Lynch Yoseph Barash MOCCASIN: a method for correcting for known and unknown confounders in RNA splicing analysis
description	Confounding factors on gene expression analysis can be analyzed by several existing tools. Here the authors develop an algorithm called MOCCASIN to correct the effect of known and unknown confounders on RNA splicing quantification.
format	article
author	Barry Slaff Caleb M. Radens Paul Jewell Anupama Jha Nicholas F. Lahens Gregory R. Grant Andrei Thomas-Tikhonenko Kristen W. Lynch Yoseph Barash
author_facet	Barry Slaff Caleb M. Radens Paul Jewell Anupama Jha Nicholas F. Lahens Gregory R. Grant Andrei Thomas-Tikhonenko Kristen W. Lynch Yoseph Barash
author_sort	Barry Slaff
title	MOCCASIN: a method for correcting for known and unknown confounders in RNA splicing analysis
title_short	MOCCASIN: a method for correcting for known and unknown confounders in RNA splicing analysis
title_full	MOCCASIN: a method for correcting for known and unknown confounders in RNA splicing analysis
title_fullStr	MOCCASIN: a method for correcting for known and unknown confounders in RNA splicing analysis
title_full_unstemmed	MOCCASIN: a method for correcting for known and unknown confounders in RNA splicing analysis
title_sort	moccasin: a method for correcting for known and unknown confounders in rna splicing analysis
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/b8ed04d2aafd4e4a8c327a67fed001a0
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MOCCASIN: a method for correcting for known and unknown confounders in RNA splicing analysis

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