In silico design and optimization of selective membranolytic anticancer peptides

Abstract Membranolytic anticancer peptides represent a potential strategy in the fight against cancer. However, our understanding of the underlying structure-activity relationships and the mechanisms driving their cell selectivity is still limited. We developed a computational approach as a step tow...

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Autores principales: Gisela Gabernet, Damian Gautschi, Alex T. Müller, Claudia S. Neuhaus, Lucas Armbrecht, Petra S. Dittrich, Jan A. Hiss, Gisbert Schneider
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/b8f8603aa1a34be985c452e189d9f671
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