In silico design and optimization of selective membranolytic anticancer peptides

Abstract Membranolytic anticancer peptides represent a potential strategy in the fight against cancer. However, our understanding of the underlying structure-activity relationships and the mechanisms driving their cell selectivity is still limited. We developed a computational approach as a step tow...

Full description

Saved in:
Bibliographic Details
Main Authors: Gisela Gabernet, Damian Gautschi, Alex T. Müller, Claudia S. Neuhaus, Lucas Armbrecht, Petra S. Dittrich, Jan A. Hiss, Gisbert Schneider
Format: article
Language:EN
Published: Nature Portfolio 2019
Subjects:
R
Q
Online Access:https://doaj.org/article/b8f8603aa1a34be985c452e189d9f671
Tags: Add Tag
No Tags, Be the first to tag this record!