FREQUENCY AND CAUSES OF BREAKTHROUGH SEIZURES AMONG ADULT PATIENTS WITH EPILEPSY DESPITE ANTIEPILEPTIC TREATMENT

Objective: To determine the frequency and causes related to the precipitation of breakthrough seizures among adult patients with epilepsy despite antiepileptic treatment. Study Design: Cross sectional analytical study. Place and Duration of Study: Pak Emirates Military Hospital Rawalpindi, fro...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Andaleeb Khan, Khurram Haq Nawaz, Saeed Arif, Muhammad Hammad Athar, Kamil Rehman Butt, Wasim Alamgir
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2019
Materias:	anti-epileptic drugs breakthrough seizures Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/b8f97df19a334788ae0799c169586482
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:b8f97df19a334788ae0799c169586482
record_format	dspace
spelling	oai:doaj.org-article:b8f97df19a334788ae0799c1695864822021-11-08T02:50:58ZFREQUENCY AND CAUSES OF BREAKTHROUGH SEIZURES AMONG ADULT PATIENTS WITH EPILEPSY DESPITE ANTIEPILEPTIC TREATMENT0030-96482411-8842https://doaj.org/article/b8f97df19a334788ae0799c1695864822019-12-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/3644/2465https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To determine the frequency and causes related to the precipitation of breakthrough seizures among adult patients with epilepsy despite antiepileptic treatment. Study Design: Cross sectional analytical study. Place and Duration of Study: Pak Emirates Military Hospital Rawalpindi, from May 2018 to Oct 2018. Methodology: The sample population comprised of 161 adult patients of epilepsy reporting to Military Hospital Rawalpindi with the epilepsy using the antiepileptic drugs (AEDs) at least for the past six months. Detailed history and physical examination was carried out for all the patients. Frequency of breakthrough seizures among this population was calculated and relationship were assessed with the precipitation of the breakthrough seizure. Results: Out of 161 patients of epileptic included in the study, 78 were male and 83 were female. Out of these 80.1% patients had breakthrough seizures. After applying the logistic regression we found that increasing age, marital status, sleep deprivation, total duration of treatment, missing one or two doses of antiepileptic drugs and watching television for long hours were strongly related to the precipitation of breakthrough seizures in our study patients. Conclusion: There was showed high frequency of breakthrough seizures in our population despite the use of AEDs. Special attention should be paid to the patients with increasing age and living alone. Education of patients regarding proper sleep, stress management, restricting TV hours and strict compliance should be done in order to prevent the phenomenon of breakthrough seizures and achieve a good control over this potentially life threatening condition.Andaleeb KhanKhurram Haq NawazSaeed ArifMuhammad Hammad AtharKamil Rehman ButtWasim AlamgirArmy Medical College Rawalpindiarticleanti-epileptic drugsbreakthrough seizuresMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 69, Iss 6, Pp 1248-1252 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	anti-epileptic drugs breakthrough seizures Medicine R Medicine (General) R5-920
spellingShingle	anti-epileptic drugs breakthrough seizures Medicine R Medicine (General) R5-920 Andaleeb Khan Khurram Haq Nawaz Saeed Arif Muhammad Hammad Athar Kamil Rehman Butt Wasim Alamgir FREQUENCY AND CAUSES OF BREAKTHROUGH SEIZURES AMONG ADULT PATIENTS WITH EPILEPSY DESPITE ANTIEPILEPTIC TREATMENT
description	Objective: To determine the frequency and causes related to the precipitation of breakthrough seizures among adult patients with epilepsy despite antiepileptic treatment. Study Design: Cross sectional analytical study. Place and Duration of Study: Pak Emirates Military Hospital Rawalpindi, from May 2018 to Oct 2018. Methodology: The sample population comprised of 161 adult patients of epilepsy reporting to Military Hospital Rawalpindi with the epilepsy using the antiepileptic drugs (AEDs) at least for the past six months. Detailed history and physical examination was carried out for all the patients. Frequency of breakthrough seizures among this population was calculated and relationship were assessed with the precipitation of the breakthrough seizure. Results: Out of 161 patients of epileptic included in the study, 78 were male and 83 were female. Out of these 80.1% patients had breakthrough seizures. After applying the logistic regression we found that increasing age, marital status, sleep deprivation, total duration of treatment, missing one or two doses of antiepileptic drugs and watching television for long hours were strongly related to the precipitation of breakthrough seizures in our study patients. Conclusion: There was showed high frequency of breakthrough seizures in our population despite the use of AEDs. Special attention should be paid to the patients with increasing age and living alone. Education of patients regarding proper sleep, stress management, restricting TV hours and strict compliance should be done in order to prevent the phenomenon of breakthrough seizures and achieve a good control over this potentially life threatening condition.
format	article
author	Andaleeb Khan Khurram Haq Nawaz Saeed Arif Muhammad Hammad Athar Kamil Rehman Butt Wasim Alamgir
author_facet	Andaleeb Khan Khurram Haq Nawaz Saeed Arif Muhammad Hammad Athar Kamil Rehman Butt Wasim Alamgir
author_sort	Andaleeb Khan
title	FREQUENCY AND CAUSES OF BREAKTHROUGH SEIZURES AMONG ADULT PATIENTS WITH EPILEPSY DESPITE ANTIEPILEPTIC TREATMENT
title_short	FREQUENCY AND CAUSES OF BREAKTHROUGH SEIZURES AMONG ADULT PATIENTS WITH EPILEPSY DESPITE ANTIEPILEPTIC TREATMENT
title_full	FREQUENCY AND CAUSES OF BREAKTHROUGH SEIZURES AMONG ADULT PATIENTS WITH EPILEPSY DESPITE ANTIEPILEPTIC TREATMENT
title_fullStr	FREQUENCY AND CAUSES OF BREAKTHROUGH SEIZURES AMONG ADULT PATIENTS WITH EPILEPSY DESPITE ANTIEPILEPTIC TREATMENT
title_full_unstemmed	FREQUENCY AND CAUSES OF BREAKTHROUGH SEIZURES AMONG ADULT PATIENTS WITH EPILEPSY DESPITE ANTIEPILEPTIC TREATMENT
title_sort	frequency and causes of breakthrough seizures among adult patients with epilepsy despite antiepileptic treatment
publisher	Army Medical College Rawalpindi
publishDate	2019
url	https://doaj.org/article/b8f97df19a334788ae0799c169586482
work_keys_str_mv	AT andaleebkhan frequencyandcausesofbreakthroughseizuresamongadultpatientswithepilepsydespiteantiepileptictreatment AT khurramhaqnawaz frequencyandcausesofbreakthroughseizuresamongadultpatientswithepilepsydespiteantiepileptictreatment AT saeedarif frequencyandcausesofbreakthroughseizuresamongadultpatientswithepilepsydespiteantiepileptictreatment AT muhammadhammadathar frequencyandcausesofbreakthroughseizuresamongadultpatientswithepilepsydespiteantiepileptictreatment AT kamilrehmanbutt frequencyandcausesofbreakthroughseizuresamongadultpatientswithepilepsydespiteantiepileptictreatment AT wasimalamgir frequencyandcausesofbreakthroughseizuresamongadultpatientswithepilepsydespiteantiepileptictreatment
_version_	1718443033065684992

FREQUENCY AND CAUSES OF BREAKTHROUGH SEIZURES AMONG ADULT PATIENTS WITH EPILEPSY DESPITE ANTIEPILEPTIC TREATMENT

Ejemplares similares