RNA-Protein Interaction Analysis of SARS-CoV-2 5′ and 3′ Untranslated Regions Reveals a Role of Lysosome-Associated Membrane Protein-2a during Viral Infection

Replication of a positive-strand RNA virus involves an RNA-protein complex consisting of viral genomic RNA, host RNA(s), virus-encoded proteins, and host proteins. Dissecting out individual components of the replication complex will help decode the mechanism of viral replication. 5′ and 3′ UTRs in...

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Autores principales:	Rohit Verma, Sandhini Saha, Shiv Kumar, Shailendra Mani, Tushar Kanti Maiti, Milan Surjit
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2021
Materias:	Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/b8fe2343272b4ced9ff635ba71173c21
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spelling	oai:doaj.org-article:b8fe2343272b4ced9ff635ba71173c212021-12-02T18:18:34ZRNA-Protein Interaction Analysis of SARS-CoV-2 5′ and 3′ Untranslated Regions Reveals a Role of Lysosome-Associated Membrane Protein-2a during Viral Infection2379-507710.1128/mSystems.00643-21https://doaj.org/article/b8fe2343272b4ced9ff635ba71173c212021-08-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mSystems.00643-21https://doaj.org/toc/2379-5077 Replication of a positive-strand RNA virus involves an RNA-protein complex consisting of viral genomic RNA, host RNA(s), virus-encoded proteins, and host proteins. Dissecting out individual components of the replication complex will help decode the mechanism of viral replication. 5′ and 3′ UTRs in positive-strand RNA viruses play essential regulatory roles in virus replication.Rohit VermaSandhini SahaShiv KumarShailendra ManiTushar Kanti MaitiMilan SurjitAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmSystems, Vol 6, Iss 4 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Microbiology QR1-502
spellingShingle	Microbiology QR1-502 Rohit Verma Sandhini Saha Shiv Kumar Shailendra Mani Tushar Kanti Maiti Milan Surjit RNA-Protein Interaction Analysis of SARS-CoV-2 5′ and 3′ Untranslated Regions Reveals a Role of Lysosome-Associated Membrane Protein-2a during Viral Infection
description	Replication of a positive-strand RNA virus involves an RNA-protein complex consisting of viral genomic RNA, host RNA(s), virus-encoded proteins, and host proteins. Dissecting out individual components of the replication complex will help decode the mechanism of viral replication. 5′ and 3′ UTRs in positive-strand RNA viruses play essential regulatory roles in virus replication.
format	article
author	Rohit Verma Sandhini Saha Shiv Kumar Shailendra Mani Tushar Kanti Maiti Milan Surjit
author_facet	Rohit Verma Sandhini Saha Shiv Kumar Shailendra Mani Tushar Kanti Maiti Milan Surjit
author_sort	Rohit Verma
title	RNA-Protein Interaction Analysis of SARS-CoV-2 5′ and 3′ Untranslated Regions Reveals a Role of Lysosome-Associated Membrane Protein-2a during Viral Infection
title_short	RNA-Protein Interaction Analysis of SARS-CoV-2 5′ and 3′ Untranslated Regions Reveals a Role of Lysosome-Associated Membrane Protein-2a during Viral Infection
title_full	RNA-Protein Interaction Analysis of SARS-CoV-2 5′ and 3′ Untranslated Regions Reveals a Role of Lysosome-Associated Membrane Protein-2a during Viral Infection
title_fullStr	RNA-Protein Interaction Analysis of SARS-CoV-2 5′ and 3′ Untranslated Regions Reveals a Role of Lysosome-Associated Membrane Protein-2a during Viral Infection
title_full_unstemmed	RNA-Protein Interaction Analysis of SARS-CoV-2 5′ and 3′ Untranslated Regions Reveals a Role of Lysosome-Associated Membrane Protein-2a during Viral Infection
title_sort	rna-protein interaction analysis of sars-cov-2 5′ and 3′ untranslated regions reveals a role of lysosome-associated membrane protein-2a during viral infection
publisher	American Society for Microbiology
publishDate	2021
url	https://doaj.org/article/b8fe2343272b4ced9ff635ba71173c21
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RNA-Protein Interaction Analysis of SARS-CoV-2 5′ and 3′ Untranslated Regions Reveals a Role of Lysosome-Associated Membrane Protein-2a during Viral Infection

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