Ribonucleotide incorporation in yeast genomic DNA shows preference for cytosine and guanosine preceded by deoxyadenosine

Ribonucleotide incorporation in yeast genomic DNA shows preference for cytosine and guanosine preceded by deoxyadenosine

Ribonucleoside monophosphates are incorporated by DNA polymerases into double-stranded DNA. Here, the authors use ribose-seq and Ribose-Map techniques to reveal that signatures and patterns of ribonucleotide incorporation in yeast mitochondrial and nuclear DNA show preference for cytosine and guanos...

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Autores principales: Sathya Balachander, Alli L. Gombolay, Taehwan Yang, Penghao Xu, Gary Newnam, Havva Keskin, Waleed M. M. El-Sayed, Anton V. Bryksin, Sijia Tao, Nicole E. Bowen, Raymond F. Schinazi, Baek Kim, Kyung Duk Koh, Fredrik O. Vannberg, Francesca Storici
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/b907278835bc4c119d07972881f86eb8
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Sumario:Ribonucleoside monophosphates are incorporated by DNA polymerases into double-stranded DNA. Here, the authors use ribose-seq and Ribose-Map techniques to reveal that signatures and patterns of ribonucleotide incorporation in yeast mitochondrial and nuclear DNA show preference for cytosine and guanosine preceded by deoxyadenosine.

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