Nanodesigned coatings obtained by plasma electrolytic oxidation of titanium implant and their cytotoxicity

The titanium implant was treated with plasma electrolytic oxidation and subsequent ionic exchange and thermal treatment in order to obtain bioactive layer consisting of titanium oxide, calcium and sodium titanates and hydroxyapatite, as confirmed by X-ray diffraction (XRD). Scanning electron microsc...

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Autores principales: Marko Magić, Božana Čolović, Saša Vasilijić, Nenad Tadić, Stevan Stojadinović, Vukoman Jokanović
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Lenguaje:EN
Publicado: SAGE Publishing 2021
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Acceso en línea:https://doaj.org/article/b90b2a191a28402a9fbcd4eab54ac173
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spelling oai:doaj.org-article:b90b2a191a28402a9fbcd4eab54ac1732021-11-16T23:03:38ZNanodesigned coatings obtained by plasma electrolytic oxidation of titanium implant and their cytotoxicity2280-800010.1177/2280800018822252https://doaj.org/article/b90b2a191a28402a9fbcd4eab54ac1732021-11-01T00:00:00Zhttps://doi.org/10.1177/2280800018822252https://doaj.org/toc/2280-8000The titanium implant was treated with plasma electrolytic oxidation and subsequent ionic exchange and thermal treatment in order to obtain bioactive layer consisting of titanium oxide, calcium and sodium titanates and hydroxyapatite, as confirmed by X-ray diffraction (XRD). Scanning electron microscopy (SEM) revealed that the given method, besides corresponding phase composition, enables suitable nanotopology for cell attachment and proliferation. Cytotoxicity investigations by MTT, LDH and propidium iodide assays and light microscopy showed that these coatings were not toxic to L929 cells.Marko MagićBožana ČolovićSaša VasilijićNenad TadićStevan StojadinovićVukoman JokanovićSAGE PublishingarticleBiotechnologyTP248.13-248.65ENJournal of Applied Biomaterials & Functional Materials, Vol 19 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biotechnology
TP248.13-248.65
spellingShingle Biotechnology
TP248.13-248.65
Marko Magić
Božana Čolović
Saša Vasilijić
Nenad Tadić
Stevan Stojadinović
Vukoman Jokanović
Nanodesigned coatings obtained by plasma electrolytic oxidation of titanium implant and their cytotoxicity
description The titanium implant was treated with plasma electrolytic oxidation and subsequent ionic exchange and thermal treatment in order to obtain bioactive layer consisting of titanium oxide, calcium and sodium titanates and hydroxyapatite, as confirmed by X-ray diffraction (XRD). Scanning electron microscopy (SEM) revealed that the given method, besides corresponding phase composition, enables suitable nanotopology for cell attachment and proliferation. Cytotoxicity investigations by MTT, LDH and propidium iodide assays and light microscopy showed that these coatings were not toxic to L929 cells.
format article
author Marko Magić
Božana Čolović
Saša Vasilijić
Nenad Tadić
Stevan Stojadinović
Vukoman Jokanović
author_facet Marko Magić
Božana Čolović
Saša Vasilijić
Nenad Tadić
Stevan Stojadinović
Vukoman Jokanović
author_sort Marko Magić
title Nanodesigned coatings obtained by plasma electrolytic oxidation of titanium implant and their cytotoxicity
title_short Nanodesigned coatings obtained by plasma electrolytic oxidation of titanium implant and their cytotoxicity
title_full Nanodesigned coatings obtained by plasma electrolytic oxidation of titanium implant and their cytotoxicity
title_fullStr Nanodesigned coatings obtained by plasma electrolytic oxidation of titanium implant and their cytotoxicity
title_full_unstemmed Nanodesigned coatings obtained by plasma electrolytic oxidation of titanium implant and their cytotoxicity
title_sort nanodesigned coatings obtained by plasma electrolytic oxidation of titanium implant and their cytotoxicity
publisher SAGE Publishing
publishDate 2021
url https://doaj.org/article/b90b2a191a28402a9fbcd4eab54ac173
work_keys_str_mv AT markomagic nanodesignedcoatingsobtainedbyplasmaelectrolyticoxidationoftitaniumimplantandtheircytotoxicity
AT bozanacolovic nanodesignedcoatingsobtainedbyplasmaelectrolyticoxidationoftitaniumimplantandtheircytotoxicity
AT sasavasilijic nanodesignedcoatingsobtainedbyplasmaelectrolyticoxidationoftitaniumimplantandtheircytotoxicity
AT nenadtadic nanodesignedcoatingsobtainedbyplasmaelectrolyticoxidationoftitaniumimplantandtheircytotoxicity
AT stevanstojadinovic nanodesignedcoatingsobtainedbyplasmaelectrolyticoxidationoftitaniumimplantandtheircytotoxicity
AT vukomanjokanovic nanodesignedcoatingsobtainedbyplasmaelectrolyticoxidationoftitaniumimplantandtheircytotoxicity
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