Curcumin prevents formation of polyglutamine aggregates by inhibiting Vps36, a component of the ESCRT-II complex.

Small molecules with antioxidative properties have been implicated in amyloid disorders. Curcumin is the active ingredient present in turmeric and known for several biological and medicinal effects. Adequate evidence substantiates the importance of curcumin in Alzheimer's disease and recent evi...

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Auteurs principaux: Meenakshi Verma, Abhishek Sharma, Swarna Naidu, Ankan Kumar Bhadra, Ritushree Kukreti, Vibha Taneja
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2012
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Accès en ligne:https://doaj.org/article/b90d63209fc649be9ea259f4be9de01b
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