Post-COVID-19 conditions in Ecuadorian patients: an observational study

Summary: Background: Post-COVID-19 disease is not yet clearly described, presenting significant clinical variability across populations and patients. This paper compares post-COVID symptoms in three patient groups with mild, moderate, and severe infections in Ecuadorian outpatients. Methods: An epi...

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Autor principal:	Fabricio González-Andrade
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2022
Materias:	post COVID-19 conditions non-hospitalised patients mild, moderate, severe clinical presentation risk factors, SARS-CoV-2 Ecuador Public aspects of medicine RA1-1270
Acceso en línea:	https://doaj.org/article/b91537902c2842ef96e978b71a1559aa
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spelling	oai:doaj.org-article:b91537902c2842ef96e978b71a1559aa2021-12-02T05:04:37ZPost-COVID-19 conditions in Ecuadorian patients: an observational study2667-193X10.1016/j.lana.2021.100088https://doaj.org/article/b91537902c2842ef96e978b71a1559aa2022-01-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2667193X21000843https://doaj.org/toc/2667-193XSummary: Background: Post-COVID-19 disease is not yet clearly described, presenting significant clinical variability across populations and patients. This paper compares post-COVID symptoms in three patient groups with mild, moderate, and severe infections in Ecuadorian outpatients. Methods: An epidemiological, observational, descriptive, and cross-sectional study was performed, and carried out in Quito, Ecuador. 1,366 non-hospitalized participants between 12 to 85 years, diagnosed with COVID-19 infection by molecular RT-PCR were included in the study. Demographic characteristics, including age groups, sex, ethnic group, work type, residence type, comorbidities, diagnosis, symptoms, and treatment were studied. Findings: 1,366 outpatient Ecuadorian patients were analysed with SARS-CoV2 infection confirmed with a PCR+ test. The mean age was 39 (± 10) years, distributed by age groups ranging between 12 and 85 years; 81.41% were between 18 and 54 years. 50.29% were men, and 49.71% were women. Interpretation: 64.3% of patients had symptoms between 4 to 6 weeks after infection, 21.1% showed ongoing symptoms between 6 to 12 weeks, and 14.6% had symptoms for more than 12 weeks. The most common symptom was fatigue in 67.3% of patients, followed by headache in 45.2%, body pain in 42.3%, and sleep disorders (insomnia, sleep apnoea, restless leg syndrome) in 36.5%. 69.3% of patients showed mild infection, 21.7% moderate, and 9.0% severe infection. On average, patients’ daily life activities showed a 6.8% mean degree of impact following infection. A sedentary lifestyle (walking less than 30 minutes a day) was the most critical risk factor (40.3%), followed by being a health worker (11.87%). Patients aged ≥55 years with HTN, CKD, smoking, and sedentary lifestyle were 4.39, 1.92, 9.19, 4.07, and 2.42 times more likely to have a severe infection level. At least 30% of patients do not feel recovered from COVID-19 infection. Funding: The author declares that the financial resources for the preparation of this research come from their self-management.Fabricio González-AndradeElsevierarticlepost COVID-19 conditionsnon-hospitalised patientsmild, moderate, severe clinical presentationrisk factors, SARS-CoV-2EcuadorPublic aspects of medicineRA1-1270ENThe Lancet Regional Health. Americas, Vol 5, Iss , Pp 100088- (2022)
institution	DOAJ
collection	DOAJ
language	EN
topic	post COVID-19 conditions non-hospitalised patients mild, moderate, severe clinical presentation risk factors, SARS-CoV-2 Ecuador Public aspects of medicine RA1-1270
spellingShingle	post COVID-19 conditions non-hospitalised patients mild, moderate, severe clinical presentation risk factors, SARS-CoV-2 Ecuador Public aspects of medicine RA1-1270 Fabricio González-Andrade Post-COVID-19 conditions in Ecuadorian patients: an observational study
description	Summary: Background: Post-COVID-19 disease is not yet clearly described, presenting significant clinical variability across populations and patients. This paper compares post-COVID symptoms in three patient groups with mild, moderate, and severe infections in Ecuadorian outpatients. Methods: An epidemiological, observational, descriptive, and cross-sectional study was performed, and carried out in Quito, Ecuador. 1,366 non-hospitalized participants between 12 to 85 years, diagnosed with COVID-19 infection by molecular RT-PCR were included in the study. Demographic characteristics, including age groups, sex, ethnic group, work type, residence type, comorbidities, diagnosis, symptoms, and treatment were studied. Findings: 1,366 outpatient Ecuadorian patients were analysed with SARS-CoV2 infection confirmed with a PCR+ test. The mean age was 39 (± 10) years, distributed by age groups ranging between 12 and 85 years; 81.41% were between 18 and 54 years. 50.29% were men, and 49.71% were women. Interpretation: 64.3% of patients had symptoms between 4 to 6 weeks after infection, 21.1% showed ongoing symptoms between 6 to 12 weeks, and 14.6% had symptoms for more than 12 weeks. The most common symptom was fatigue in 67.3% of patients, followed by headache in 45.2%, body pain in 42.3%, and sleep disorders (insomnia, sleep apnoea, restless leg syndrome) in 36.5%. 69.3% of patients showed mild infection, 21.7% moderate, and 9.0% severe infection. On average, patients’ daily life activities showed a 6.8% mean degree of impact following infection. A sedentary lifestyle (walking less than 30 minutes a day) was the most critical risk factor (40.3%), followed by being a health worker (11.87%). Patients aged ≥55 years with HTN, CKD, smoking, and sedentary lifestyle were 4.39, 1.92, 9.19, 4.07, and 2.42 times more likely to have a severe infection level. At least 30% of patients do not feel recovered from COVID-19 infection. Funding: The author declares that the financial resources for the preparation of this research come from their self-management.
format	article
author	Fabricio González-Andrade
author_facet	Fabricio González-Andrade
author_sort	Fabricio González-Andrade
title	Post-COVID-19 conditions in Ecuadorian patients: an observational study
title_short	Post-COVID-19 conditions in Ecuadorian patients: an observational study
title_full	Post-COVID-19 conditions in Ecuadorian patients: an observational study
title_fullStr	Post-COVID-19 conditions in Ecuadorian patients: an observational study
title_full_unstemmed	Post-COVID-19 conditions in Ecuadorian patients: an observational study
title_sort	post-covid-19 conditions in ecuadorian patients: an observational study
publisher	Elsevier
publishDate	2022
url	https://doaj.org/article/b91537902c2842ef96e978b71a1559aa
work_keys_str_mv	AT fabriciogonzalezandrade postcovid19conditionsinecuadorianpatientsanobservationalstudy
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Post-COVID-19 conditions in Ecuadorian patients: an observational study

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