ATR is a multifunctional regulator of male mouse meiosis
ATR kinase is required for meiosis in non-mammalian model organisms. Here the authors demonstrate, using a tissue-specific knockout approach, that ATR is also essential for male meiosis in mouse, regulating meiotic recombination and synapsis.
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Autores principales: | Alexander Widger, Shantha K. Mahadevaiah, Julian Lange, Elias ElInati, Jasmin Zohren, Takayuki Hirota, Sarai Pacheco, Andros Maldonado-Linares, Marcello Stanzione, Obah Ojarikre, Valdone Maciulyte, Dirk G. de Rooij, Attila Tóth, Ignasi Roig, Scott Keeney, James M.A. Turner |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/b92089ad88aa43c8bc4181f628f431ba |
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