“Q-markers targeted screening” strategy for comprehensive qualitative and quantitative analysis in fingerprints of Angelica dahurica with chemometric methods

Angelica dahurica is a famous functional food and herb. To guarantee quality of A. dahurica, a strategy “Q-markers targeted screening” was successfully developed by sufficient extraction of compounds and the targeted screening of qualitative and quantitative markers calculated through chemometric me...

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Autores principales:	Fang-Yuan Gao, Hai-Yan Chen, Yu-Sha Luo, Ji-Kuai Chen, Lang Yan, Jiang-Bo Zhu, Guo-Rong Fan, Ting-Ting Zhou
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Angelica dahurica Q-markers targeted screening Qualitative markers Quantitative markers Accelerated solvent extraction Chemometric analysis Nutrition. Foods and food supply TX341-641 Food processing and manufacture TP368-456
Acceso en línea:	https://doaj.org/article/b928273247194ae888274eab199b5141
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id	oai:doaj.org-article:b928273247194ae888274eab199b5141
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spelling	oai:doaj.org-article:b928273247194ae888274eab199b51412021-11-18T04:51:25Z“Q-markers targeted screening” strategy for comprehensive qualitative and quantitative analysis in fingerprints of Angelica dahurica with chemometric methods2590-157510.1016/j.fochx.2021.100162https://doaj.org/article/b928273247194ae888274eab199b51412021-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S259015752100050Xhttps://doaj.org/toc/2590-1575Angelica dahurica is a famous functional food and herb. To guarantee quality of A. dahurica, a strategy “Q-markers targeted screening” was successfully developed by sufficient extraction of compounds and the targeted screening of qualitative and quantitative markers calculated through chemometric methods based fingerprints. Accelerated solvent extraction was selected due to its prominent advantages exhibiting the maximum extraction yields and varieties of compounds and especially excellent reproducibility (RSD < 1). After extraction, the fingerprints of A. dahuricae samples were established. For the preliminary herb authenticity, the targeted screening of 23 quantitative markers were performed by similarity analysis and hierarchical cluster analysis based on the fingerprints, which were identified by liquid chromatography tandem mass spectrometry (LC-MS). Subsequently, for further quality control, the targeted screening of nine quantitative markers were done by similarity analysis & linear discriminant analysis, which were determined by LC. Lastly, the strategy was successfully applied to quality assessment of A. dahurica samples.Fang-Yuan GaoHai-Yan ChenYu-Sha LuoJi-Kuai ChenLang YanJiang-Bo ZhuGuo-Rong FanTing-Ting ZhouElsevierarticleAngelica dahuricaQ-markers targeted screeningQualitative markersQuantitative markersAccelerated solvent extractionChemometric analysisNutrition. Foods and food supplyTX341-641Food processing and manufactureTP368-456ENFood Chemistry: X, Vol 12, Iss , Pp 100162- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Angelica dahurica Q-markers targeted screening Qualitative markers Quantitative markers Accelerated solvent extraction Chemometric analysis Nutrition. Foods and food supply TX341-641 Food processing and manufacture TP368-456
spellingShingle	Angelica dahurica Q-markers targeted screening Qualitative markers Quantitative markers Accelerated solvent extraction Chemometric analysis Nutrition. Foods and food supply TX341-641 Food processing and manufacture TP368-456 Fang-Yuan Gao Hai-Yan Chen Yu-Sha Luo Ji-Kuai Chen Lang Yan Jiang-Bo Zhu Guo-Rong Fan Ting-Ting Zhou “Q-markers targeted screening” strategy for comprehensive qualitative and quantitative analysis in fingerprints of Angelica dahurica with chemometric methods
description	Angelica dahurica is a famous functional food and herb. To guarantee quality of A. dahurica, a strategy “Q-markers targeted screening” was successfully developed by sufficient extraction of compounds and the targeted screening of qualitative and quantitative markers calculated through chemometric methods based fingerprints. Accelerated solvent extraction was selected due to its prominent advantages exhibiting the maximum extraction yields and varieties of compounds and especially excellent reproducibility (RSD < 1). After extraction, the fingerprints of A. dahuricae samples were established. For the preliminary herb authenticity, the targeted screening of 23 quantitative markers were performed by similarity analysis and hierarchical cluster analysis based on the fingerprints, which were identified by liquid chromatography tandem mass spectrometry (LC-MS). Subsequently, for further quality control, the targeted screening of nine quantitative markers were done by similarity analysis & linear discriminant analysis, which were determined by LC. Lastly, the strategy was successfully applied to quality assessment of A. dahurica samples.
format	article
author	Fang-Yuan Gao Hai-Yan Chen Yu-Sha Luo Ji-Kuai Chen Lang Yan Jiang-Bo Zhu Guo-Rong Fan Ting-Ting Zhou
author_facet	Fang-Yuan Gao Hai-Yan Chen Yu-Sha Luo Ji-Kuai Chen Lang Yan Jiang-Bo Zhu Guo-Rong Fan Ting-Ting Zhou
author_sort	Fang-Yuan Gao
title	“Q-markers targeted screening” strategy for comprehensive qualitative and quantitative analysis in fingerprints of Angelica dahurica with chemometric methods
title_short	“Q-markers targeted screening” strategy for comprehensive qualitative and quantitative analysis in fingerprints of Angelica dahurica with chemometric methods
title_full	“Q-markers targeted screening” strategy for comprehensive qualitative and quantitative analysis in fingerprints of Angelica dahurica with chemometric methods
title_fullStr	“Q-markers targeted screening” strategy for comprehensive qualitative and quantitative analysis in fingerprints of Angelica dahurica with chemometric methods
title_full_unstemmed	“Q-markers targeted screening” strategy for comprehensive qualitative and quantitative analysis in fingerprints of Angelica dahurica with chemometric methods
title_sort	“q-markers targeted screening” strategy for comprehensive qualitative and quantitative analysis in fingerprints of angelica dahurica with chemometric methods
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/b928273247194ae888274eab199b5141
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“Q-markers targeted screening” strategy for comprehensive qualitative and quantitative analysis in fingerprints of Angelica dahurica with chemometric methods

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