A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome

Carpal tunnel syndrome (CTS) is caused by entrapment of the median nerve at the wrist. Here, Wiberg et al. perform a GWAS for CTS in the UK Biobank cohort and identify 16 genetic loci, and find a causal relationship between short stature and CTS risk using Mendelian randomisation.

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Autores principales:	Akira Wiberg, Michael Ng, Annina B. Schmid, Robert W. Smillie, Georgios Baskozos, Michael V. Holmes, K. Künnapuu, R. Mägi, David L. Bennett, Dominic Furniss
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b928570826824d63b1fd9927dee82655
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spelling	oai:doaj.org-article:b928570826824d63b1fd9927dee826552021-12-02T17:32:55ZA genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome10.1038/s41467-019-08993-62041-1723https://doaj.org/article/b928570826824d63b1fd9927dee826552019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08993-6https://doaj.org/toc/2041-1723Carpal tunnel syndrome (CTS) is caused by entrapment of the median nerve at the wrist. Here, Wiberg et al. perform a GWAS for CTS in the UK Biobank cohort and identify 16 genetic loci, and find a causal relationship between short stature and CTS risk using Mendelian randomisation.Akira WibergMichael NgAnnina B. SchmidRobert W. SmillieGeorgios BaskozosMichael V. HolmesK. KünnapuuR. MägiDavid L. BennettDominic FurnissNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Akira Wiberg Michael Ng Annina B. Schmid Robert W. Smillie Georgios Baskozos Michael V. Holmes K. Künnapuu R. Mägi David L. Bennett Dominic Furniss A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome
description	Carpal tunnel syndrome (CTS) is caused by entrapment of the median nerve at the wrist. Here, Wiberg et al. perform a GWAS for CTS in the UK Biobank cohort and identify 16 genetic loci, and find a causal relationship between short stature and CTS risk using Mendelian randomisation.
format	article
author	Akira Wiberg Michael Ng Annina B. Schmid Robert W. Smillie Georgios Baskozos Michael V. Holmes K. Künnapuu R. Mägi David L. Bennett Dominic Furniss
author_facet	Akira Wiberg Michael Ng Annina B. Schmid Robert W. Smillie Georgios Baskozos Michael V. Holmes K. Künnapuu R. Mägi David L. Bennett Dominic Furniss
author_sort	Akira Wiberg
title	A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome
title_short	A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome
title_full	A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome
title_fullStr	A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome
title_full_unstemmed	A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome
title_sort	genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/b928570826824d63b1fd9927dee82655
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A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome

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