Nano-palladium is a cellular catalyst for in vivo chemistry

Palladium (Pd) is a well-known catalyst in organic chemistry but its use in nanomedicine is limited. Here, the authors design a Pd nanoparticle that triggers the activation of an antitumour prodrugin vivo, which shows efficacy and improves toxicity compared to traditional solvent- and nanoparticle-d...

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Autores principales:	Miles A. Miller, Bjorn Askevold, Hannes Mikula, Rainer H. Kohler, David Pirovich, Ralph Weissleder
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b929185b46444f18bedc3e0efd655654
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spelling	oai:doaj.org-article:b929185b46444f18bedc3e0efd6556542021-12-02T14:42:18ZNano-palladium is a cellular catalyst for in vivo chemistry10.1038/ncomms159062041-1723https://doaj.org/article/b929185b46444f18bedc3e0efd6556542017-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms15906https://doaj.org/toc/2041-1723Palladium (Pd) is a well-known catalyst in organic chemistry but its use in nanomedicine is limited. Here, the authors design a Pd nanoparticle that triggers the activation of an antitumour prodrugin vivo, which shows efficacy and improves toxicity compared to traditional solvent- and nanoparticle-drug formulations.Miles A. MillerBjorn AskevoldHannes MikulaRainer H. KohlerDavid PirovichRalph WeisslederNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Miles A. Miller Bjorn Askevold Hannes Mikula Rainer H. Kohler David Pirovich Ralph Weissleder Nano-palladium is a cellular catalyst for in vivo chemistry
description	Palladium (Pd) is a well-known catalyst in organic chemistry but its use in nanomedicine is limited. Here, the authors design a Pd nanoparticle that triggers the activation of an antitumour prodrugin vivo, which shows efficacy and improves toxicity compared to traditional solvent- and nanoparticle-drug formulations.
format	article
author	Miles A. Miller Bjorn Askevold Hannes Mikula Rainer H. Kohler David Pirovich Ralph Weissleder
author_facet	Miles A. Miller Bjorn Askevold Hannes Mikula Rainer H. Kohler David Pirovich Ralph Weissleder
author_sort	Miles A. Miller
title	Nano-palladium is a cellular catalyst for in vivo chemistry
title_short	Nano-palladium is a cellular catalyst for in vivo chemistry
title_full	Nano-palladium is a cellular catalyst for in vivo chemistry
title_fullStr	Nano-palladium is a cellular catalyst for in vivo chemistry
title_full_unstemmed	Nano-palladium is a cellular catalyst for in vivo chemistry
title_sort	nano-palladium is a cellular catalyst for in vivo chemistry
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/b929185b46444f18bedc3e0efd655654
work_keys_str_mv	AT milesamiller nanopalladiumisacellularcatalystforinvivochemistry AT bjornaskevold nanopalladiumisacellularcatalystforinvivochemistry AT hannesmikula nanopalladiumisacellularcatalystforinvivochemistry AT rainerhkohler nanopalladiumisacellularcatalystforinvivochemistry AT davidpirovich nanopalladiumisacellularcatalystforinvivochemistry AT ralphweissleder nanopalladiumisacellularcatalystforinvivochemistry
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Nano-palladium is a cellular catalyst for in vivo chemistry

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