New Steroidal Saponins Isolated from the Rhizomes of <i>Paris mairei</i>
The genus <i>Paris</i> is an excellent source of steroidal saponins that exhibit various bioactivities. <i>Paris mairei</i> is a unique species and has been widely used as folk medicine in Southwest China for a long time. With the help of chemical methods and modern spectra a...
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| Autores principales: | , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
MDPI AG
2021
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/b929b14d73444735952ca84585801955 |
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| Sumario: | The genus <i>Paris</i> is an excellent source of steroidal saponins that exhibit various bioactivities. <i>Paris mairei</i> is a unique species and has been widely used as folk medicine in Southwest China for a long time. With the help of chemical methods and modern spectra analysis, five new steroidal saponins, pamaiosides A–E (<b>1</b>–<b>5</b>), along with five known steroidal saponins <b>6</b>–<b>10</b>, were isolated from the rhizomes of <i>Paris mairei</i>. The cytotoxicity of all the new saponins was evaluated against human pancreatic adenocarcinoma PANC-1 and BxPC3 cell lines. |
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