New Steroidal Saponins Isolated from the Rhizomes of Paris mairei

The genus Paris is an excellent source of steroidal saponins that exhibit various bioactivities. Paris mairei is a unique species and has been widely used as folk medicine in Southwest China for a long time. With the help of chemical methods and modern spectra a...

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Autores principales:	Yang Liu, Pengcheng Qiu, Minchang Wang, Yunyang Lu, Hao He, Haifeng Tang, Bang-Le Zhang
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	<i>Paris mairei</i> steroidal saponins spirostane saponin 15-oxo-18-nor-spirost cytotoxicity Organic chemistry QD241-441
Acceso en línea:	https://doaj.org/article/b929b14d73444735952ca84585801955
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spelling	oai:doaj.org-article:b929b14d73444735952ca845858019552021-11-11T18:23:31ZNew Steroidal Saponins Isolated from the Rhizomes of <i>Paris mairei</i>10.3390/molecules262163661420-3049https://doaj.org/article/b929b14d73444735952ca845858019552021-10-01T00:00:00Zhttps://www.mdpi.com/1420-3049/26/21/6366https://doaj.org/toc/1420-3049The genus <i>Paris</i> is an excellent source of steroidal saponins that exhibit various bioactivities. <i>Paris mairei</i> is a unique species and has been widely used as folk medicine in Southwest China for a long time. With the help of chemical methods and modern spectra analysis, five new steroidal saponins, pamaiosides A–E (<b>1</b>–<b>5</b>), along with five known steroidal saponins <b>6</b>–<b>10</b>, were isolated from the rhizomes of <i>Paris mairei</i>. The cytotoxicity of all the new saponins was evaluated against human pancreatic adenocarcinoma PANC-1 and BxPC3 cell lines.Yang LiuPengcheng QiuMinchang WangYunyang LuHao HeHaifeng TangBang-Le ZhangMDPI AGarticle<i>Paris mairei</i>steroidal saponinsspirostane saponin15-oxo-18-nor-spirostcytotoxicityOrganic chemistryQD241-441ENMolecules, Vol 26, Iss 6366, p 6366 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	<i>Paris mairei</i> steroidal saponins spirostane saponin 15-oxo-18-nor-spirost cytotoxicity Organic chemistry QD241-441
spellingShingle	<i>Paris mairei</i> steroidal saponins spirostane saponin 15-oxo-18-nor-spirost cytotoxicity Organic chemistry QD241-441 Yang Liu Pengcheng Qiu Minchang Wang Yunyang Lu Hao He Haifeng Tang Bang-Le Zhang New Steroidal Saponins Isolated from the Rhizomes of <i>Paris mairei</i>
description	The genus <i>Paris</i> is an excellent source of steroidal saponins that exhibit various bioactivities. <i>Paris mairei</i> is a unique species and has been widely used as folk medicine in Southwest China for a long time. With the help of chemical methods and modern spectra analysis, five new steroidal saponins, pamaiosides A–E (<b>1</b>–<b>5</b>), along with five known steroidal saponins <b>6</b>–<b>10</b>, were isolated from the rhizomes of <i>Paris mairei</i>. The cytotoxicity of all the new saponins was evaluated against human pancreatic adenocarcinoma PANC-1 and BxPC3 cell lines.
format	article
author	Yang Liu Pengcheng Qiu Minchang Wang Yunyang Lu Hao He Haifeng Tang Bang-Le Zhang
author_facet	Yang Liu Pengcheng Qiu Minchang Wang Yunyang Lu Hao He Haifeng Tang Bang-Le Zhang
author_sort	Yang Liu
title	New Steroidal Saponins Isolated from the Rhizomes of <i>Paris mairei</i>
title_short	New Steroidal Saponins Isolated from the Rhizomes of <i>Paris mairei</i>
title_full	New Steroidal Saponins Isolated from the Rhizomes of <i>Paris mairei</i>
title_fullStr	New Steroidal Saponins Isolated from the Rhizomes of <i>Paris mairei</i>
title_full_unstemmed	New Steroidal Saponins Isolated from the Rhizomes of <i>Paris mairei</i>
title_sort	new steroidal saponins isolated from the rhizomes of <i>paris mairei</i>
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/b929b14d73444735952ca84585801955
work_keys_str_mv	AT yangliu newsteroidalsaponinsisolatedfromtherhizomesofiparismaireii AT pengchengqiu newsteroidalsaponinsisolatedfromtherhizomesofiparismaireii AT minchangwang newsteroidalsaponinsisolatedfromtherhizomesofiparismaireii AT yunyanglu newsteroidalsaponinsisolatedfromtherhizomesofiparismaireii AT haohe newsteroidalsaponinsisolatedfromtherhizomesofiparismaireii AT haifengtang newsteroidalsaponinsisolatedfromtherhizomesofiparismaireii AT banglezhang newsteroidalsaponinsisolatedfromtherhizomesofiparismaireii
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New Steroidal Saponins Isolated from the Rhizomes of <i>Paris mairei</i>

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