Insights into the Implications of Coexisting Type 2 Inflammatory Diseases

Justin P McCormick, Jivianne T Lee Department of Head and Neck Surgery, University of California Los Angeles David Geffen School of Medicine, Los Angeles, CA, USACorrespondence: Jivianne T LeeDepartment of Head and Neck Surgery, University of California Los Angeles, David Geffen School of Medicine,...

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Autores principales:	McCormick JP, Lee JT
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	type 2 inflammation th2 inflammation asthma atopic dermatitis eosinophilic esophagitis chronic rhinosinusitis Pathology RB1-214 Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/b9316eb72d1145d382d280e404f12818
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spelling	oai:doaj.org-article:b9316eb72d1145d382d280e404f128182021-12-02T16:34:31ZInsights into the Implications of Coexisting Type 2 Inflammatory Diseases1178-7031https://doaj.org/article/b9316eb72d1145d382d280e404f128182021-08-01T00:00:00Zhttps://www.dovepress.com/insights-into-the-implications-of-coexisting-type-2-inflammatory-disea-peer-reviewed-fulltext-article-JIRhttps://doaj.org/toc/1178-7031Justin P McCormick, Jivianne T Lee Department of Head and Neck Surgery, University of California Los Angeles David Geffen School of Medicine, Los Angeles, CA, USACorrespondence: Jivianne T LeeDepartment of Head and Neck Surgery, University of California Los Angeles, David Geffen School of Medicine, Los Angeles, CA, USAEmail jtlee@mednet.ucla.eduAbstract: The role of type 2 inflammation in the pathogenesis of certain human diseases is an area of active investigation. Certain asthma, atopic dermatitis, eosinophilic esophagitis, and chronic rhinosinusitis phenotypes are characterized by a Th2 predominant inflammatory pathway and are frequently associated with comorbid conditions in patients. The purpose of this article is to review the evidence behind concurrent Th2-mediated diseases and explore how the presence of these comorbid conditions affect patient and disease outcomes.Keywords: type 2 inflammation, Th2 inflammation, asthma, atopic dermatitis, eosinophilic esophagitis, chronic rhinosinusitisMcCormick JPLee JTDove Medical Pressarticletype 2 inflammationth2 inflammationasthmaatopic dermatitiseosinophilic esophagitischronic rhinosinusitisPathologyRB1-214Therapeutics. PharmacologyRM1-950ENJournal of Inflammation Research, Vol Volume 14, Pp 4259-4266 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	type 2 inflammation th2 inflammation asthma atopic dermatitis eosinophilic esophagitis chronic rhinosinusitis Pathology RB1-214 Therapeutics. Pharmacology RM1-950
spellingShingle	type 2 inflammation th2 inflammation asthma atopic dermatitis eosinophilic esophagitis chronic rhinosinusitis Pathology RB1-214 Therapeutics. Pharmacology RM1-950 McCormick JP Lee JT Insights into the Implications of Coexisting Type 2 Inflammatory Diseases
description	Justin P McCormick, Jivianne T Lee Department of Head and Neck Surgery, University of California Los Angeles David Geffen School of Medicine, Los Angeles, CA, USACorrespondence: Jivianne T LeeDepartment of Head and Neck Surgery, University of California Los Angeles, David Geffen School of Medicine, Los Angeles, CA, USAEmail jtlee@mednet.ucla.eduAbstract: The role of type 2 inflammation in the pathogenesis of certain human diseases is an area of active investigation. Certain asthma, atopic dermatitis, eosinophilic esophagitis, and chronic rhinosinusitis phenotypes are characterized by a Th2 predominant inflammatory pathway and are frequently associated with comorbid conditions in patients. The purpose of this article is to review the evidence behind concurrent Th2-mediated diseases and explore how the presence of these comorbid conditions affect patient and disease outcomes.Keywords: type 2 inflammation, Th2 inflammation, asthma, atopic dermatitis, eosinophilic esophagitis, chronic rhinosinusitis
format	article
author	McCormick JP Lee JT
author_facet	McCormick JP Lee JT
author_sort	McCormick JP
title	Insights into the Implications of Coexisting Type 2 Inflammatory Diseases
title_short	Insights into the Implications of Coexisting Type 2 Inflammatory Diseases
title_full	Insights into the Implications of Coexisting Type 2 Inflammatory Diseases
title_fullStr	Insights into the Implications of Coexisting Type 2 Inflammatory Diseases
title_full_unstemmed	Insights into the Implications of Coexisting Type 2 Inflammatory Diseases
title_sort	insights into the implications of coexisting type 2 inflammatory diseases
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/b9316eb72d1145d382d280e404f12818
work_keys_str_mv	AT mccormickjp insightsintotheimplicationsofcoexistingtype2inflammatorydiseases AT leejt insightsintotheimplicationsofcoexistingtype2inflammatorydiseases
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Insights into the Implications of Coexisting Type 2 Inflammatory Diseases

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