Chromatin-remodelling factor Brg1 regulates myocardial proliferation and regeneration in zebrafish

Chromatin-remodelling factor Brg1 regulates myocardial proliferation and regeneration in zebrafish

The adult zebrafish heart is capable of regeneration but the molecular mechanisms are poorly understood. Here the authors show that chromatin remodeling factor Brg1 represses cyclin-dependent kinase inhibitors to promote myocardial regeneration.

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Autores principales: Chenglu Xiao, Lu Gao, Yu Hou, Congfei Xu, Nannan Chang, Fang Wang, Keping Hu, Aibin He, Ying Luo, Jun Wang, Jinrong Peng, Fuchou Tang, Xiaojun Zhu, Jing-Wei Xiong
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/b93453a1fef44a088b1bca315686928d
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spelling oai:doaj.org-article:b93453a1fef44a088b1bca315686928d2021-12-02T16:49:43ZChromatin-remodelling factor Brg1 regulates myocardial proliferation and regeneration in zebrafish10.1038/ncomms137872041-1723https://doaj.org/article/b93453a1fef44a088b1bca315686928d2016-12-01T00:00:00Zhttps://doi.org/10.1038/ncomms13787https://doaj.org/toc/2041-1723The adult zebrafish heart is capable of regeneration but the molecular mechanisms are poorly understood. Here the authors show that chromatin remodeling factor Brg1 represses cyclin-dependent kinase inhibitors to promote myocardial regeneration.Chenglu XiaoLu GaoYu HouCongfei XuNannan ChangFang WangKeping HuAibin HeYing LuoJun WangJinrong PengFuchou TangXiaojun ZhuJing-Wei XiongNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Chenglu Xiao
Lu Gao
Yu Hou
Congfei Xu
Nannan Chang
Fang Wang
Keping Hu
Aibin He
Ying Luo
Jun Wang
Jinrong Peng
Fuchou Tang
Xiaojun Zhu
Jing-Wei Xiong
Chromatin-remodelling factor Brg1 regulates myocardial proliferation and regeneration in zebrafish
description The adult zebrafish heart is capable of regeneration but the molecular mechanisms are poorly understood. Here the authors show that chromatin remodeling factor Brg1 represses cyclin-dependent kinase inhibitors to promote myocardial regeneration.
format article
author Chenglu Xiao
Lu Gao
Yu Hou
Congfei Xu
Nannan Chang
Fang Wang
Keping Hu
Aibin He
Ying Luo
Jun Wang
Jinrong Peng
Fuchou Tang
Xiaojun Zhu
Jing-Wei Xiong
author_facet Chenglu Xiao
Lu Gao
Yu Hou
Congfei Xu
Nannan Chang
Fang Wang
Keping Hu
Aibin He
Ying Luo
Jun Wang
Jinrong Peng
Fuchou Tang
Xiaojun Zhu
Jing-Wei Xiong
author_sort Chenglu Xiao
title Chromatin-remodelling factor Brg1 regulates myocardial proliferation and regeneration in zebrafish
title_short Chromatin-remodelling factor Brg1 regulates myocardial proliferation and regeneration in zebrafish
title_full Chromatin-remodelling factor Brg1 regulates myocardial proliferation and regeneration in zebrafish
title_fullStr Chromatin-remodelling factor Brg1 regulates myocardial proliferation and regeneration in zebrafish
title_full_unstemmed Chromatin-remodelling factor Brg1 regulates myocardial proliferation and regeneration in zebrafish
title_sort chromatin-remodelling factor brg1 regulates myocardial proliferation and regeneration in zebrafish
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/b93453a1fef44a088b1bca315686928d
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AT congfeixu chromatinremodellingfactorbrg1regulatesmyocardialproliferationandregenerationinzebrafish
AT nannanchang chromatinremodellingfactorbrg1regulatesmyocardialproliferationandregenerationinzebrafish
AT fangwang chromatinremodellingfactorbrg1regulatesmyocardialproliferationandregenerationinzebrafish
AT kepinghu chromatinremodellingfactorbrg1regulatesmyocardialproliferationandregenerationinzebrafish
AT aibinhe chromatinremodellingfactorbrg1regulatesmyocardialproliferationandregenerationinzebrafish
AT yingluo chromatinremodellingfactorbrg1regulatesmyocardialproliferationandregenerationinzebrafish
AT junwang chromatinremodellingfactorbrg1regulatesmyocardialproliferationandregenerationinzebrafish
AT jinrongpeng chromatinremodellingfactorbrg1regulatesmyocardialproliferationandregenerationinzebrafish
AT fuchoutang chromatinremodellingfactorbrg1regulatesmyocardialproliferationandregenerationinzebrafish
AT xiaojunzhu chromatinremodellingfactorbrg1regulatesmyocardialproliferationandregenerationinzebrafish
AT jingweixiong chromatinremodellingfactorbrg1regulatesmyocardialproliferationandregenerationinzebrafish
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