Missing Links: the Role of Primates in Understanding the Human Microbiome

ABSTRACT The gut microbiome can influence host energy balances and metabolic programming. While this information is valuable in a disease context, it also has important implications for understanding host energetics from an ecological and evolutionary perspective. Here I argue that gut microbial inf...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autor principal:	Katherine R. Amato
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2019
Materias:	gut microbiome life history primate Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/b93602db739943679eddbc7c9b5eecf2
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:b93602db739943679eddbc7c9b5eecf2
record_format	dspace
spelling	oai:doaj.org-article:b93602db739943679eddbc7c9b5eecf22021-12-02T19:47:35ZMissing Links: the Role of Primates in Understanding the Human Microbiome10.1128/mSystems.00165-192379-5077https://doaj.org/article/b93602db739943679eddbc7c9b5eecf22019-06-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mSystems.00165-19https://doaj.org/toc/2379-5077ABSTRACT The gut microbiome can influence host energy balances and metabolic programming. While this information is valuable in a disease context, it also has important implications for understanding host energetics from an ecological and evolutionary perspective. Here I argue that gut microbial influences on host life history—the timing of events that make up an organism's life—are an overlooked but robust area of study given that variation in life history is linked directly to host energetic budgets and allocation patterns. Additionally, while cultural influences on life history complicate the exploration of these links in humans, nonhuman primates represent an alternative system in which more robust associations can be made. By integrating human and nonhuman primate microbiome research within the context of life history theory, we will be able to more effectively pinpoint microbial contributions to host phenotypes. This information will improve our understanding of host-microbe interactions in health and disease and will transform the fields of ecology and evolution more generally.Katherine R. AmatoAmerican Society for Microbiologyarticlegut microbiomelife historyprimateMicrobiologyQR1-502ENmSystems, Vol 4, Iss 3 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	gut microbiome life history primate Microbiology QR1-502
spellingShingle	gut microbiome life history primate Microbiology QR1-502 Katherine R. Amato Missing Links: the Role of Primates in Understanding the Human Microbiome
description	ABSTRACT The gut microbiome can influence host energy balances and metabolic programming. While this information is valuable in a disease context, it also has important implications for understanding host energetics from an ecological and evolutionary perspective. Here I argue that gut microbial influences on host life history—the timing of events that make up an organism's life—are an overlooked but robust area of study given that variation in life history is linked directly to host energetic budgets and allocation patterns. Additionally, while cultural influences on life history complicate the exploration of these links in humans, nonhuman primates represent an alternative system in which more robust associations can be made. By integrating human and nonhuman primate microbiome research within the context of life history theory, we will be able to more effectively pinpoint microbial contributions to host phenotypes. This information will improve our understanding of host-microbe interactions in health and disease and will transform the fields of ecology and evolution more generally.
format	article
author	Katherine R. Amato
author_facet	Katherine R. Amato
author_sort	Katherine R. Amato
title	Missing Links: the Role of Primates in Understanding the Human Microbiome
title_short	Missing Links: the Role of Primates in Understanding the Human Microbiome
title_full	Missing Links: the Role of Primates in Understanding the Human Microbiome
title_fullStr	Missing Links: the Role of Primates in Understanding the Human Microbiome
title_full_unstemmed	Missing Links: the Role of Primates in Understanding the Human Microbiome
title_sort	missing links: the role of primates in understanding the human microbiome
publisher	American Society for Microbiology
publishDate	2019
url	https://doaj.org/article/b93602db739943679eddbc7c9b5eecf2
work_keys_str_mv	AT katherineramato missinglinkstheroleofprimatesinunderstandingthehumanmicrobiome
_version_	1718375986029920256

Missing Links: the Role of Primates in Understanding the Human Microbiome

Ejemplares similares