Replicability and heterogeneity of awake unrestrained canine FMRI responses.

Replicability and heterogeneity of awake unrestrained canine FMRI responses.

Previously, we demonstrated the possibility of fMRI in two awake and unrestrained dogs. Here, we determined the replicability and heterogeneity of these results in an additional 11 dogs for a total of 13 subjects. Based on an anatomically placed region-of-interest, we compared the caudate response t...

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Autores principales: Gregory S Berns, Andrew Brooks, Mark Spivak
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/b9472d3463fc4177a278dc52608ec69a
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spelling oai:doaj.org-article:b9472d3463fc4177a278dc52608ec69a2021-11-18T08:43:31ZReplicability and heterogeneity of awake unrestrained canine FMRI responses.1932-620310.1371/journal.pone.0081698https://doaj.org/article/b9472d3463fc4177a278dc52608ec69a2013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24324719/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203Previously, we demonstrated the possibility of fMRI in two awake and unrestrained dogs. Here, we determined the replicability and heterogeneity of these results in an additional 11 dogs for a total of 13 subjects. Based on an anatomically placed region-of-interest, we compared the caudate response to a hand signal indicating the imminent availability of a food reward to a hand signal indicating no reward. 8 of 13 dogs had a positive differential caudate response to the signal indicating reward. The mean differential caudate response was 0.09%, which was similar to a comparable human study. These results show that canine fMRI is reliable and can be done with minimal stress to the dogs.Gregory S BernsAndrew BrooksMark SpivakPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 12, p e81698 (2013)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Gregory S Berns
Andrew Brooks
Mark Spivak
Replicability and heterogeneity of awake unrestrained canine FMRI responses.
description Previously, we demonstrated the possibility of fMRI in two awake and unrestrained dogs. Here, we determined the replicability and heterogeneity of these results in an additional 11 dogs for a total of 13 subjects. Based on an anatomically placed region-of-interest, we compared the caudate response to a hand signal indicating the imminent availability of a food reward to a hand signal indicating no reward. 8 of 13 dogs had a positive differential caudate response to the signal indicating reward. The mean differential caudate response was 0.09%, which was similar to a comparable human study. These results show that canine fMRI is reliable and can be done with minimal stress to the dogs.
format article
author Gregory S Berns
Andrew Brooks
Mark Spivak
author_facet Gregory S Berns
Andrew Brooks
Mark Spivak
author_sort Gregory S Berns
title Replicability and heterogeneity of awake unrestrained canine FMRI responses.
title_short Replicability and heterogeneity of awake unrestrained canine FMRI responses.
title_full Replicability and heterogeneity of awake unrestrained canine FMRI responses.
title_fullStr Replicability and heterogeneity of awake unrestrained canine FMRI responses.
title_full_unstemmed Replicability and heterogeneity of awake unrestrained canine FMRI responses.
title_sort replicability and heterogeneity of awake unrestrained canine fmri responses.
publisher Public Library of Science (PLoS)
publishDate 2013
url https://doaj.org/article/b9472d3463fc4177a278dc52608ec69a
work_keys_str_mv AT gregorysberns replicabilityandheterogeneityofawakeunrestrainedcaninefmriresponses
AT andrewbrooks replicabilityandheterogeneityofawakeunrestrainedcaninefmriresponses
AT markspivak replicabilityandheterogeneityofawakeunrestrainedcaninefmriresponses
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