Malaria Diagnosis in Non-Endemic Settings: The European Experience in the Last 22 Years

Accurate, prompt, and reliable tools for the diagnosis of malaria are crucial for tracking the successes or drawbacks of control and elimination efforts, and for future programs aimed at global malaria eradication. Although microscopy remains the gold standard method, the number of imported malaria...

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Autores principales:	Adriana Calderaro, Sara Montecchini, Mirko Buttrini, Giovanna Piccolo, Sabina Rossi, Maria Cristina Arcangeletti, Benedetta Farina, Flora De Conto, Carlo Chezzi
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	imported malaria diagnosis molecular methods Europe polymerase chain reaction Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/b94a7db149a840d0b8091b04b905aec7
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spelling	oai:doaj.org-article:b94a7db149a840d0b8091b04b905aec72021-11-25T18:24:42ZMalaria Diagnosis in Non-Endemic Settings: The European Experience in the Last 22 Years10.3390/microorganisms91122652076-2607https://doaj.org/article/b94a7db149a840d0b8091b04b905aec72021-10-01T00:00:00Zhttps://www.mdpi.com/2076-2607/9/11/2265https://doaj.org/toc/2076-2607Accurate, prompt, and reliable tools for the diagnosis of malaria are crucial for tracking the successes or drawbacks of control and elimination efforts, and for future programs aimed at global malaria eradication. Although microscopy remains the gold standard method, the number of imported malaria cases and the risk of reappearance of autochthonous cases stimulated several laboratories located in European countries to evaluate methods and algorithms suited to non-endemic settings, where skilled microscopists are not always available. In this review, an overview of the field evaluation and a comparison of the methods used for the diagnosis of malaria by European laboratories is reported, showing that the development of numerous innovations is continuous. In particular, the combination of rapid diagnostic tests and molecular assays with microscopy represents a reliable system for the early diagnosis of malaria in non-endemic settings.Adriana CalderaroSara MontecchiniMirko ButtriniGiovanna PiccoloSabina RossiMaria Cristina ArcangelettiBenedetta FarinaFlora De ContoCarlo ChezziMDPI AGarticleimported malariadiagnosismolecular methodsEuropepolymerase chain reactionBiology (General)QH301-705.5ENMicroorganisms, Vol 9, Iss 2265, p 2265 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	imported malaria diagnosis molecular methods Europe polymerase chain reaction Biology (General) QH301-705.5
spellingShingle	imported malaria diagnosis molecular methods Europe polymerase chain reaction Biology (General) QH301-705.5 Adriana Calderaro Sara Montecchini Mirko Buttrini Giovanna Piccolo Sabina Rossi Maria Cristina Arcangeletti Benedetta Farina Flora De Conto Carlo Chezzi Malaria Diagnosis in Non-Endemic Settings: The European Experience in the Last 22 Years
description	Accurate, prompt, and reliable tools for the diagnosis of malaria are crucial for tracking the successes or drawbacks of control and elimination efforts, and for future programs aimed at global malaria eradication. Although microscopy remains the gold standard method, the number of imported malaria cases and the risk of reappearance of autochthonous cases stimulated several laboratories located in European countries to evaluate methods and algorithms suited to non-endemic settings, where skilled microscopists are not always available. In this review, an overview of the field evaluation and a comparison of the methods used for the diagnosis of malaria by European laboratories is reported, showing that the development of numerous innovations is continuous. In particular, the combination of rapid diagnostic tests and molecular assays with microscopy represents a reliable system for the early diagnosis of malaria in non-endemic settings.
format	article
author	Adriana Calderaro Sara Montecchini Mirko Buttrini Giovanna Piccolo Sabina Rossi Maria Cristina Arcangeletti Benedetta Farina Flora De Conto Carlo Chezzi
author_facet	Adriana Calderaro Sara Montecchini Mirko Buttrini Giovanna Piccolo Sabina Rossi Maria Cristina Arcangeletti Benedetta Farina Flora De Conto Carlo Chezzi
author_sort	Adriana Calderaro
title	Malaria Diagnosis in Non-Endemic Settings: The European Experience in the Last 22 Years
title_short	Malaria Diagnosis in Non-Endemic Settings: The European Experience in the Last 22 Years
title_full	Malaria Diagnosis in Non-Endemic Settings: The European Experience in the Last 22 Years
title_fullStr	Malaria Diagnosis in Non-Endemic Settings: The European Experience in the Last 22 Years
title_full_unstemmed	Malaria Diagnosis in Non-Endemic Settings: The European Experience in the Last 22 Years
title_sort	malaria diagnosis in non-endemic settings: the european experience in the last 22 years
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/b94a7db149a840d0b8091b04b905aec7
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Malaria Diagnosis in Non-Endemic Settings: The European Experience in the Last 22 Years

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