CopyCatchers are versatile active genetic elements that detect and quantify inter-homolog somatic gene conversion

CRISPR-based genetic elements can copy themselves across host genomes. Here the authors introduce CopyCatcher, a gene-drive related system for detecting and quantifying somatic gene conversion events.

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Auteurs principaux: Zhiqian Li, Nimi Marcel, Sushil Devkota, Ankush Auradkar, Stephen M. Hedrick, Valentino M. Gantz, Ethan Bier
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/b94ecd06f7bb42bcb6d8bcbcc6d0a9f1
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spelling oai:doaj.org-article:b94ecd06f7bb42bcb6d8bcbcc6d0a9f12021-12-02T14:35:33ZCopyCatchers are versatile active genetic elements that detect and quantify inter-homolog somatic gene conversion10.1038/s41467-021-22927-12041-1723https://doaj.org/article/b94ecd06f7bb42bcb6d8bcbcc6d0a9f12021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22927-1https://doaj.org/toc/2041-1723CRISPR-based genetic elements can copy themselves across host genomes. Here the authors introduce CopyCatcher, a gene-drive related system for detecting and quantifying somatic gene conversion events.Zhiqian LiNimi MarcelSushil DevkotaAnkush AuradkarStephen M. HedrickValentino M. GantzEthan BierNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Zhiqian Li
Nimi Marcel
Sushil Devkota
Ankush Auradkar
Stephen M. Hedrick
Valentino M. Gantz
Ethan Bier
CopyCatchers are versatile active genetic elements that detect and quantify inter-homolog somatic gene conversion
description CRISPR-based genetic elements can copy themselves across host genomes. Here the authors introduce CopyCatcher, a gene-drive related system for detecting and quantifying somatic gene conversion events.
format article
author Zhiqian Li
Nimi Marcel
Sushil Devkota
Ankush Auradkar
Stephen M. Hedrick
Valentino M. Gantz
Ethan Bier
author_facet Zhiqian Li
Nimi Marcel
Sushil Devkota
Ankush Auradkar
Stephen M. Hedrick
Valentino M. Gantz
Ethan Bier
author_sort Zhiqian Li
title CopyCatchers are versatile active genetic elements that detect and quantify inter-homolog somatic gene conversion
title_short CopyCatchers are versatile active genetic elements that detect and quantify inter-homolog somatic gene conversion
title_full CopyCatchers are versatile active genetic elements that detect and quantify inter-homolog somatic gene conversion
title_fullStr CopyCatchers are versatile active genetic elements that detect and quantify inter-homolog somatic gene conversion
title_full_unstemmed CopyCatchers are versatile active genetic elements that detect and quantify inter-homolog somatic gene conversion
title_sort copycatchers are versatile active genetic elements that detect and quantify inter-homolog somatic gene conversion
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/b94ecd06f7bb42bcb6d8bcbcc6d0a9f1
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AT sushildevkota copycatchersareversatileactivegeneticelementsthatdetectandquantifyinterhomologsomaticgeneconversion
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AT stephenmhedrick copycatchersareversatileactivegeneticelementsthatdetectandquantifyinterhomologsomaticgeneconversion
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AT ethanbier copycatchersareversatileactivegeneticelementsthatdetectandquantifyinterhomologsomaticgeneconversion
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