Bone corticalization requires local SOCS3 activity and is promoted by androgen action via interleukin-6

The strength of long bones is determined by coalescence of trabeculae during corticalization. Here the authors show that this process is regulated by SOCS3 via a mechanism dependent on IL-6 and expression of sex hormones.

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Detalles Bibliográficos
Autores principales: Dae-Chul Cho, Holly J. Brennan, Rachelle W. Johnson, Ingrid J. Poulton, Jonathan H. Gooi, Brett A. Tonkin, Narelle E. McGregor, Emma C. Walker, David J. Handelsman, T. J. Martin, Natalie A. Sims
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/b957b83bc219453cadc23acf2a9623c9
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