Integrative pan-cancer analysis of MEK1 aberrations and the potential clinical implications

Abstract Alterations of mitogen-activated protein kinase kinase 1 (MEK1) are commonly associated with tumorigenesis, and MEK1 is thought to be a suitable targeted therapy for various cancers. However, abnormal MEK1 alterations and their relevant clinical implications are unknown. Our research compre...

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Autores principales: Zhiyang Zhou, Bi Peng, Juanni Li, Kewa Gao, Yuan Cai, Zhijie Xu, Yuanliang Yan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/b9595cdb825245dc94645c30ef9b2c5e
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