The Effectiveness of Vitamin A on the Symptoms of Brucellosis

BACKGROUND AND OBJECTIVE: Vitamin A in the immune system is considered as an anti-inflammatory vitamin that has anti-infective effects in infectious diseases. Therefore, this study was performed to evaluate the effectiveness of vitamin A as one of the complementary therapies in the treatment of bruc...

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Autores principales:	N Ahmadvand, N Zarinfar, M Soofian
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2021
Materias:	brucellosis vitamin a treatment outcome. Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/b962ddf625724ea8ac547760f90590af
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spelling	oai:doaj.org-article:b962ddf625724ea8ac547760f90590af2021-11-29T07:40:49ZThe Effectiveness of Vitamin A on the Symptoms of Brucellosis1561-41072251-7170https://doaj.org/article/b962ddf625724ea8ac547760f90590af2021-03-01T00:00:00Zhttp://jbums.org/article-1-9569-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170BACKGROUND AND OBJECTIVE: Vitamin A in the immune system is considered as an anti-inflammatory vitamin that has anti-infective effects in infectious diseases. Therefore, this study was performed to evaluate the effectiveness of vitamin A as one of the complementary therapies in the treatment of brucellosis. METHODS: In this experimental study, 110 people were selected as brucellosis patients based on serological test and were placed in two groups of control and intervention. In addition to the usual drugs for the treatment of brucellosis, patients in the intervention group received oral vitamin A at a dose of 25,000 units pre day for 6 weeks, and patients in the control group did not receive vitamin A. After the intervention, the response to treatment was evaluated based on the number of days of fever, chills, sweating, arthralgia, myalgia, anorexia, chronicity and recurrence using standard methods in the two groups. FINDINGS: In terms of days with fever (14.72±27.61 vs. 53.45±141.14), sweating (19.27±28.98 vs. 61.09±142.35), arthralgia (56±96.83 vs. 53.45±158.18), myalgia (13.45±27.23 vs. 52.36±141.44) and anorexia (13.30±47.39 vs. 51.81±129.8), a significant decrease was observed in the intervention group compared to the control (p<0.05). There was no difference between the intervention and control groups in terms of chills (p=0.122). The recurrence rate in the control and intervention groups was 25.5% and 7.3%, respectively, and the chronicity rate was 3.6% and 0%, respectively, which was statistically significant (p<0.05). CONCLUSION: Based on the results of the study, it can be said that vitamin A leads to faster improvement of brucellosis symptoms and it can be used as a complementary treatment for brucellosis.N AhmadvandN ZarinfarM SoofianBabol University of Medical Sciencesarticlebrucellosisvitamin atreatment outcome.MedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 23, Iss 1, Pp 252-258 (2021)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	brucellosis vitamin a treatment outcome. Medicine R Medicine (General) R5-920
spellingShingle	brucellosis vitamin a treatment outcome. Medicine R Medicine (General) R5-920 N Ahmadvand N Zarinfar M Soofian The Effectiveness of Vitamin A on the Symptoms of Brucellosis
description	BACKGROUND AND OBJECTIVE: Vitamin A in the immune system is considered as an anti-inflammatory vitamin that has anti-infective effects in infectious diseases. Therefore, this study was performed to evaluate the effectiveness of vitamin A as one of the complementary therapies in the treatment of brucellosis. METHODS: In this experimental study, 110 people were selected as brucellosis patients based on serological test and were placed in two groups of control and intervention. In addition to the usual drugs for the treatment of brucellosis, patients in the intervention group received oral vitamin A at a dose of 25,000 units pre day for 6 weeks, and patients in the control group did not receive vitamin A. After the intervention, the response to treatment was evaluated based on the number of days of fever, chills, sweating, arthralgia, myalgia, anorexia, chronicity and recurrence using standard methods in the two groups. FINDINGS: In terms of days with fever (14.72±27.61 vs. 53.45±141.14), sweating (19.27±28.98 vs. 61.09±142.35), arthralgia (56±96.83 vs. 53.45±158.18), myalgia (13.45±27.23 vs. 52.36±141.44) and anorexia (13.30±47.39 vs. 51.81±129.8), a significant decrease was observed in the intervention group compared to the control (p<0.05). There was no difference between the intervention and control groups in terms of chills (p=0.122). The recurrence rate in the control and intervention groups was 25.5% and 7.3%, respectively, and the chronicity rate was 3.6% and 0%, respectively, which was statistically significant (p<0.05). CONCLUSION: Based on the results of the study, it can be said that vitamin A leads to faster improvement of brucellosis symptoms and it can be used as a complementary treatment for brucellosis.
format	article
author	N Ahmadvand N Zarinfar M Soofian
author_facet	N Ahmadvand N Zarinfar M Soofian
author_sort	N Ahmadvand
title	The Effectiveness of Vitamin A on the Symptoms of Brucellosis
title_short	The Effectiveness of Vitamin A on the Symptoms of Brucellosis
title_full	The Effectiveness of Vitamin A on the Symptoms of Brucellosis
title_fullStr	The Effectiveness of Vitamin A on the Symptoms of Brucellosis
title_full_unstemmed	The Effectiveness of Vitamin A on the Symptoms of Brucellosis
title_sort	effectiveness of vitamin a on the symptoms of brucellosis
publisher	Babol University of Medical Sciences
publishDate	2021
url	https://doaj.org/article/b962ddf625724ea8ac547760f90590af
work_keys_str_mv	AT nahmadvand theeffectivenessofvitaminaonthesymptomsofbrucellosis AT nzarinfar theeffectivenessofvitaminaonthesymptomsofbrucellosis AT msoofian theeffectivenessofvitaminaonthesymptomsofbrucellosis AT nahmadvand effectivenessofvitaminaonthesymptomsofbrucellosis AT nzarinfar effectivenessofvitaminaonthesymptomsofbrucellosis AT msoofian effectivenessofvitaminaonthesymptomsofbrucellosis
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The Effectiveness of Vitamin A on the Symptoms of Brucellosis

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