Three-year results of a modified photodynamic therapy procedure (Ironing PDT) for age-related macular degeneration patients with large lesions

Tsuyoshi Otsuji,1 Kenichiro Sho,2 Akiko Tsumura,1 Naoko Koike,1 Tetsuya Nishimura,1 Kanji Takahashi2 1Department of Ophthalmology, Kansai Medical University, Takii Hospital, 2Department of Ophthalmology, Kansai Medical University, Hirakata Hospital, Osaka, Japan Background: To evaluate the effect...

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Autores principales:	Otsuji T, Sho K, Tsumura A, Koike N, Nishimura T, Takahashi K
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2016
Materias:	AMD PDT Ironing PDT Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/b970113aa8934c86b8d8f8ff8f1b87d9
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spelling	oai:doaj.org-article:b970113aa8934c86b8d8f8ff8f1b87d92021-12-02T00:11:52ZThree-year results of a modified photodynamic therapy procedure (Ironing PDT) for age-related macular degeneration patients with large lesions1177-5483https://doaj.org/article/b970113aa8934c86b8d8f8ff8f1b87d92016-03-01T00:00:00Zhttps://www.dovepress.com/three-year-results-of-a-modified-photodynamic-therapy-procedure-ironin-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Tsuyoshi Otsuji,1 Kenichiro Sho,2 Akiko Tsumura,1 Naoko Koike,1 Tetsuya Nishimura,1 Kanji Takahashi2 1Department of Ophthalmology, Kansai Medical University, Takii Hospital, 2Department of Ophthalmology, Kansai Medical University, Hirakata Hospital, Osaka, Japan Background: To evaluate the effect of photodynamic therapy (PDT) using a modified procedure on exudative age-related macular degeneration having been conventionally difficult to treat.  Methods: The medical records of eight consecutive patients (eight eyes) with age-related macular degeneration treated with modified PDT were reviewed retrospectively. Modified PDT was used for the lesions that could not be covered by conventional use of PDT, either because the lesion was too large or too close to the optic disc. A moving PDT laser spot at constant speed, for 83 seconds, was used to cover the entire lesion, and was named “Ironing PDT.” This retrospective study was performed with informed patient consent. It was approved by the Institutional Review Board of Kansai Medical University.Results: No exudation could be found 36 months after treatment in five eyes (62.5%). There was no significant difference between the best-corrected visual acuity before PDT (0.95 logMAR) and after PDT (1.09 logMAR). The logMAR best-corrected visual acuity was improved in one eye, maintained in five eyes, and deteriorated in two eyes.  Conclusion: Ironing PDT decreased subfoveal fluid and preserved visual acuity in some patients with age-related macular degeneration difficult to treat with conventional therapy. Keywords: AMD, PCV, PDT, Ironing PDT, modified PDT, large lesionsOtsuji TSho KTsumura AKoike NNishimura TTakahashi KDove Medical PressarticleAMDPDTIroning PDTOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2016, Iss Issue 1, Pp 431-436 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	AMD PDT Ironing PDT Ophthalmology RE1-994
spellingShingle	AMD PDT Ironing PDT Ophthalmology RE1-994 Otsuji T Sho K Tsumura A Koike N Nishimura T Takahashi K Three-year results of a modified photodynamic therapy procedure (Ironing PDT) for age-related macular degeneration patients with large lesions
description	Tsuyoshi Otsuji,1 Kenichiro Sho,2 Akiko Tsumura,1 Naoko Koike,1 Tetsuya Nishimura,1 Kanji Takahashi2 1Department of Ophthalmology, Kansai Medical University, Takii Hospital, 2Department of Ophthalmology, Kansai Medical University, Hirakata Hospital, Osaka, Japan Background: To evaluate the effect of photodynamic therapy (PDT) using a modified procedure on exudative age-related macular degeneration having been conventionally difficult to treat.  Methods: The medical records of eight consecutive patients (eight eyes) with age-related macular degeneration treated with modified PDT were reviewed retrospectively. Modified PDT was used for the lesions that could not be covered by conventional use of PDT, either because the lesion was too large or too close to the optic disc. A moving PDT laser spot at constant speed, for 83 seconds, was used to cover the entire lesion, and was named “Ironing PDT.” This retrospective study was performed with informed patient consent. It was approved by the Institutional Review Board of Kansai Medical University.Results: No exudation could be found 36 months after treatment in five eyes (62.5%). There was no significant difference between the best-corrected visual acuity before PDT (0.95 logMAR) and after PDT (1.09 logMAR). The logMAR best-corrected visual acuity was improved in one eye, maintained in five eyes, and deteriorated in two eyes.  Conclusion: Ironing PDT decreased subfoveal fluid and preserved visual acuity in some patients with age-related macular degeneration difficult to treat with conventional therapy. Keywords: AMD, PCV, PDT, Ironing PDT, modified PDT, large lesions
format	article
author	Otsuji T Sho K Tsumura A Koike N Nishimura T Takahashi K
author_facet	Otsuji T Sho K Tsumura A Koike N Nishimura T Takahashi K
author_sort	Otsuji T
title	Three-year results of a modified photodynamic therapy procedure (Ironing PDT) for age-related macular degeneration patients with large lesions
title_short	Three-year results of a modified photodynamic therapy procedure (Ironing PDT) for age-related macular degeneration patients with large lesions
title_full	Three-year results of a modified photodynamic therapy procedure (Ironing PDT) for age-related macular degeneration patients with large lesions
title_fullStr	Three-year results of a modified photodynamic therapy procedure (Ironing PDT) for age-related macular degeneration patients with large lesions
title_full_unstemmed	Three-year results of a modified photodynamic therapy procedure (Ironing PDT) for age-related macular degeneration patients with large lesions
title_sort	three-year results of a modified photodynamic therapy procedure (ironing pdt) for age-related macular degeneration patients with large lesions
publisher	Dove Medical Press
publishDate	2016
url	https://doaj.org/article/b970113aa8934c86b8d8f8ff8f1b87d9
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Three-year results of a modified photodynamic therapy procedure (Ironing PDT) for age-related macular degeneration patients with large lesions

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