Analysis of the effects of spaceflight and local administration of thrombopoietin to a femoral defect injury on distal skeletal sites

Abstract With increased human presence in space, bone loss and fractures will occur. Thrombopoietin (TPO) is a recently patented bone healing agent. Here, we investigated the systemic effects of TPO on mice subjected to spaceflight and sustaining a bone fracture. Forty, 9-week-old, male, C57BL/6 J w...

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Bibliographic Details
Main Authors: Ariane Zamarioli, Zachery R. Campbell, Kevin A. Maupin, Paul J. Childress, Joao P. B. Ximenez, Gremah Adam, Nabarun Chakraborty, Aarti Gautam, Rasha Hammamieh, Melissa A. Kacena
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/b975b97ec90645fda468f236688c4df4
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