Flexible simultaneous mesoscale two-photon imaging of neural activity at high speeds

Functional brain imaging with two-photon microscopy is limited by a tradeoff between imaging area and acquisition speed. Here, the authors present Quadroscope, a flexible microscope which allows for simultaneous video rate acquisition of four independently targetable brain regions across 5 mm.

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Autores principales:	Mitchell Clough, Ichun Anderson Chen, Seong-Wook Park, Allison M. Ahrens, Jeffrey N. Stirman, Spencer L. Smith, Jerry L. Chen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b981c71532914106a9b1e5778371edc0
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spelling	oai:doaj.org-article:b981c71532914106a9b1e5778371edc02021-11-21T12:35:41ZFlexible simultaneous mesoscale two-photon imaging of neural activity at high speeds10.1038/s41467-021-26737-32041-1723https://doaj.org/article/b981c71532914106a9b1e5778371edc02021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26737-3https://doaj.org/toc/2041-1723Functional brain imaging with two-photon microscopy is limited by a tradeoff between imaging area and acquisition speed. Here, the authors present Quadroscope, a flexible microscope which allows for simultaneous video rate acquisition of four independently targetable brain regions across 5 mm.Mitchell CloughIchun Anderson ChenSeong-Wook ParkAllison M. AhrensJeffrey N. StirmanSpencer L. SmithJerry L. ChenNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mitchell Clough Ichun Anderson Chen Seong-Wook Park Allison M. Ahrens Jeffrey N. Stirman Spencer L. Smith Jerry L. Chen Flexible simultaneous mesoscale two-photon imaging of neural activity at high speeds
description	Functional brain imaging with two-photon microscopy is limited by a tradeoff between imaging area and acquisition speed. Here, the authors present Quadroscope, a flexible microscope which allows for simultaneous video rate acquisition of four independently targetable brain regions across 5 mm.
format	article
author	Mitchell Clough Ichun Anderson Chen Seong-Wook Park Allison M. Ahrens Jeffrey N. Stirman Spencer L. Smith Jerry L. Chen
author_facet	Mitchell Clough Ichun Anderson Chen Seong-Wook Park Allison M. Ahrens Jeffrey N. Stirman Spencer L. Smith Jerry L. Chen
author_sort	Mitchell Clough
title	Flexible simultaneous mesoscale two-photon imaging of neural activity at high speeds
title_short	Flexible simultaneous mesoscale two-photon imaging of neural activity at high speeds
title_full	Flexible simultaneous mesoscale two-photon imaging of neural activity at high speeds
title_fullStr	Flexible simultaneous mesoscale two-photon imaging of neural activity at high speeds
title_full_unstemmed	Flexible simultaneous mesoscale two-photon imaging of neural activity at high speeds
title_sort	flexible simultaneous mesoscale two-photon imaging of neural activity at high speeds
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/b981c71532914106a9b1e5778371edc0
work_keys_str_mv	AT mitchellclough flexiblesimultaneousmesoscaletwophotonimagingofneuralactivityathighspeeds AT ichunandersonchen flexiblesimultaneousmesoscaletwophotonimagingofneuralactivityathighspeeds AT seongwookpark flexiblesimultaneousmesoscaletwophotonimagingofneuralactivityathighspeeds AT allisonmahrens flexiblesimultaneousmesoscaletwophotonimagingofneuralactivityathighspeeds AT jeffreynstirman flexiblesimultaneousmesoscaletwophotonimagingofneuralactivityathighspeeds AT spencerlsmith flexiblesimultaneousmesoscaletwophotonimagingofneuralactivityathighspeeds AT jerrylchen flexiblesimultaneousmesoscaletwophotonimagingofneuralactivityathighspeeds
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Flexible simultaneous mesoscale two-photon imaging of neural activity at high speeds

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