Expansion within the CYP71D subfamily drives the heterocyclization of tanshinones synthesis in Salvia miltiorrhiza
Salvia miltiorrhiza is a medicinal plant that can produce the bioactive tanshinones. Here, the authors report the improved genome assembly and reveal the possible roles of three CYP71Ds in catalyzing the reactions leading to the formation of the characteristic furan D-ring of transhinones.
Guardado en:
| Autores principales: | , , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2021
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/b983d580b4a346649fadf2ec2f3efd5b |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:b983d580b4a346649fadf2ec2f3efd5b |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:b983d580b4a346649fadf2ec2f3efd5b2021-12-02T13:27:30ZExpansion within the CYP71D subfamily drives the heterocyclization of tanshinones synthesis in Salvia miltiorrhiza10.1038/s41467-021-20959-12041-1723https://doaj.org/article/b983d580b4a346649fadf2ec2f3efd5b2021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-20959-1https://doaj.org/toc/2041-1723Salvia miltiorrhiza is a medicinal plant that can produce the bioactive tanshinones. Here, the authors report the improved genome assembly and reveal the possible roles of three CYP71Ds in catalyzing the reactions leading to the formation of the characteristic furan D-ring of transhinones.Ying MaGuanghong CuiTong ChenXiaohui MaRuishan WangBaolong JinJian YangLiping KangJinfu TangChangjiangsheng LaiYanan WangYujun ZhaoYe ShenWen ZengReuben J. PetersXiaoquan QiJuan GuoLuqi HuangNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Ying Ma Guanghong Cui Tong Chen Xiaohui Ma Ruishan Wang Baolong Jin Jian Yang Liping Kang Jinfu Tang Changjiangsheng Lai Yanan Wang Yujun Zhao Ye Shen Wen Zeng Reuben J. Peters Xiaoquan Qi Juan Guo Luqi Huang Expansion within the CYP71D subfamily drives the heterocyclization of tanshinones synthesis in Salvia miltiorrhiza |
| description |
Salvia miltiorrhiza is a medicinal plant that can produce the bioactive tanshinones. Here, the authors report the improved genome assembly and reveal the possible roles of three CYP71Ds in catalyzing the reactions leading to the formation of the characteristic furan D-ring of transhinones. |
| format |
article |
| author |
Ying Ma Guanghong Cui Tong Chen Xiaohui Ma Ruishan Wang Baolong Jin Jian Yang Liping Kang Jinfu Tang Changjiangsheng Lai Yanan Wang Yujun Zhao Ye Shen Wen Zeng Reuben J. Peters Xiaoquan Qi Juan Guo Luqi Huang |
| author_facet |
Ying Ma Guanghong Cui Tong Chen Xiaohui Ma Ruishan Wang Baolong Jin Jian Yang Liping Kang Jinfu Tang Changjiangsheng Lai Yanan Wang Yujun Zhao Ye Shen Wen Zeng Reuben J. Peters Xiaoquan Qi Juan Guo Luqi Huang |
| author_sort |
Ying Ma |
| title |
Expansion within the CYP71D subfamily drives the heterocyclization of tanshinones synthesis in Salvia miltiorrhiza |
| title_short |
Expansion within the CYP71D subfamily drives the heterocyclization of tanshinones synthesis in Salvia miltiorrhiza |
| title_full |
Expansion within the CYP71D subfamily drives the heterocyclization of tanshinones synthesis in Salvia miltiorrhiza |
| title_fullStr |
Expansion within the CYP71D subfamily drives the heterocyclization of tanshinones synthesis in Salvia miltiorrhiza |
| title_full_unstemmed |
Expansion within the CYP71D subfamily drives the heterocyclization of tanshinones synthesis in Salvia miltiorrhiza |
| title_sort |
expansion within the cyp71d subfamily drives the heterocyclization of tanshinones synthesis in salvia miltiorrhiza |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/b983d580b4a346649fadf2ec2f3efd5b |
| work_keys_str_mv |
AT yingma expansionwithinthecyp71dsubfamilydrivestheheterocyclizationoftanshinonessynthesisinsalviamiltiorrhiza AT guanghongcui expansionwithinthecyp71dsubfamilydrivestheheterocyclizationoftanshinonessynthesisinsalviamiltiorrhiza AT tongchen expansionwithinthecyp71dsubfamilydrivestheheterocyclizationoftanshinonessynthesisinsalviamiltiorrhiza AT xiaohuima expansionwithinthecyp71dsubfamilydrivestheheterocyclizationoftanshinonessynthesisinsalviamiltiorrhiza AT ruishanwang expansionwithinthecyp71dsubfamilydrivestheheterocyclizationoftanshinonessynthesisinsalviamiltiorrhiza AT baolongjin expansionwithinthecyp71dsubfamilydrivestheheterocyclizationoftanshinonessynthesisinsalviamiltiorrhiza AT jianyang expansionwithinthecyp71dsubfamilydrivestheheterocyclizationoftanshinonessynthesisinsalviamiltiorrhiza AT lipingkang expansionwithinthecyp71dsubfamilydrivestheheterocyclizationoftanshinonessynthesisinsalviamiltiorrhiza AT jinfutang expansionwithinthecyp71dsubfamilydrivestheheterocyclizationoftanshinonessynthesisinsalviamiltiorrhiza AT changjiangshenglai expansionwithinthecyp71dsubfamilydrivestheheterocyclizationoftanshinonessynthesisinsalviamiltiorrhiza AT yananwang expansionwithinthecyp71dsubfamilydrivestheheterocyclizationoftanshinonessynthesisinsalviamiltiorrhiza AT yujunzhao expansionwithinthecyp71dsubfamilydrivestheheterocyclizationoftanshinonessynthesisinsalviamiltiorrhiza AT yeshen expansionwithinthecyp71dsubfamilydrivestheheterocyclizationoftanshinonessynthesisinsalviamiltiorrhiza AT wenzeng expansionwithinthecyp71dsubfamilydrivestheheterocyclizationoftanshinonessynthesisinsalviamiltiorrhiza AT reubenjpeters expansionwithinthecyp71dsubfamilydrivestheheterocyclizationoftanshinonessynthesisinsalviamiltiorrhiza AT xiaoquanqi expansionwithinthecyp71dsubfamilydrivestheheterocyclizationoftanshinonessynthesisinsalviamiltiorrhiza AT juanguo expansionwithinthecyp71dsubfamilydrivestheheterocyclizationoftanshinonessynthesisinsalviamiltiorrhiza AT luqihuang expansionwithinthecyp71dsubfamilydrivestheheterocyclizationoftanshinonessynthesisinsalviamiltiorrhiza |
| _version_ |
1718392997493604352 |