Super-Enhancers and Broad H3K4me3 Domains Form Complex Gene Regulatory Circuits Involving Chromatin Interactions
Abstract Stretched histone regions, such as super-enhancers and broad H3K4me3 domains, are associated with maintenance of cell identity and cancer. We connected super-enhancers and broad H3K4me3 domains in the K562 chronic myelogenous leukemia cell line as well as the MCF-7 breast cancer cell line w...
Guardado en:
Autores principales: | Fan Cao, Yiwen Fang, Hong Kee Tan, Yufen Goh, Jocelyn Yeen Hui Choy, Bryan Thean Howe Koh, Jiong Hao Tan, Nicolas Bertin, Aroul Ramadass, Ewan Hunter, Jayne Green, Matthew Salter, Alexandre Akoulitchev, Wilson Wang, Wee Joo Chng, Daniel G. Tenen, Melissa J. Fullwood |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/b9841c5e788645b792bb546cfc9f0e3c |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
The broad role of Nkx3.2 in the development of the zebrafish axial skeleton.
por: Laura Waldmann, et al.
Publicado: (2021) -
CRISPR-Cas3 induces broad and unidirectional genome editing in human cells
por: Hiroyuki Morisaka, et al.
Publicado: (2019) -
Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization
por: Nikolas Friedrich, et al.
Publicado: (2021) -
A Comparative Analysis of Super-Enhancers and Broad H3K4me3 Domains in Pig, Human, and Mouse Tissues
por: Yanling Peng, et al.
Publicado: (2021) -
Risk factors, molecular epidemiology and outcomes of ertapenem-resistant, carbapenem-susceptible Enterobacteriaceae: a case-case-control study.
por: Jocelyn Teo, et al.
Publicado: (2012)