Macrophage-released ADAMTS1 promotes muscle stem cell activation

Satellite cells are crucial for growth and regeneration of skeletal muscle. Here the authors show that in response to muscle injury, macrophages secrete Adamts1, which induces satellite cell activation by modulating Notch1 signaling.

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Detalles Bibliográficos
Autores principales:	Hongqing Du, Chung-Hsuan Shih, Michael N. Wosczyna, Alisa A. Mueller, Joonseok Cho, Abhishek Aggarwal, Thomas A. Rando, Brian J. Feldman
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b985b4346d2b4425bb7a38b75908eb78
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spelling	oai:doaj.org-article:b985b4346d2b4425bb7a38b75908eb782021-12-02T17:01:24ZMacrophage-released ADAMTS1 promotes muscle stem cell activation10.1038/s41467-017-00522-72041-1723https://doaj.org/article/b985b4346d2b4425bb7a38b75908eb782017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00522-7https://doaj.org/toc/2041-1723Satellite cells are crucial for growth and regeneration of skeletal muscle. Here the authors show that in response to muscle injury, macrophages secrete Adamts1, which induces satellite cell activation by modulating Notch1 signaling.Hongqing DuChung-Hsuan ShihMichael N. WosczynaAlisa A. MuellerJoonseok ChoAbhishek AggarwalThomas A. RandoBrian J. FeldmanNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hongqing Du Chung-Hsuan Shih Michael N. Wosczyna Alisa A. Mueller Joonseok Cho Abhishek Aggarwal Thomas A. Rando Brian J. Feldman Macrophage-released ADAMTS1 promotes muscle stem cell activation
description	Satellite cells are crucial for growth and regeneration of skeletal muscle. Here the authors show that in response to muscle injury, macrophages secrete Adamts1, which induces satellite cell activation by modulating Notch1 signaling.
format	article
author	Hongqing Du Chung-Hsuan Shih Michael N. Wosczyna Alisa A. Mueller Joonseok Cho Abhishek Aggarwal Thomas A. Rando Brian J. Feldman
author_facet	Hongqing Du Chung-Hsuan Shih Michael N. Wosczyna Alisa A. Mueller Joonseok Cho Abhishek Aggarwal Thomas A. Rando Brian J. Feldman
author_sort	Hongqing Du
title	Macrophage-released ADAMTS1 promotes muscle stem cell activation
title_short	Macrophage-released ADAMTS1 promotes muscle stem cell activation
title_full	Macrophage-released ADAMTS1 promotes muscle stem cell activation
title_fullStr	Macrophage-released ADAMTS1 promotes muscle stem cell activation
title_full_unstemmed	Macrophage-released ADAMTS1 promotes muscle stem cell activation
title_sort	macrophage-released adamts1 promotes muscle stem cell activation
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/b985b4346d2b4425bb7a38b75908eb78
work_keys_str_mv	AT hongqingdu macrophagereleasedadamts1promotesmusclestemcellactivation AT chunghsuanshih macrophagereleasedadamts1promotesmusclestemcellactivation AT michaelnwosczyna macrophagereleasedadamts1promotesmusclestemcellactivation AT alisaamueller macrophagereleasedadamts1promotesmusclestemcellactivation AT joonseokcho macrophagereleasedadamts1promotesmusclestemcellactivation AT abhishekaggarwal macrophagereleasedadamts1promotesmusclestemcellactivation AT thomasarando macrophagereleasedadamts1promotesmusclestemcellactivation AT brianjfeldman macrophagereleasedadamts1promotesmusclestemcellactivation
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Macrophage-released ADAMTS1 promotes muscle stem cell activation

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