Macrophage-released ADAMTS1 promotes muscle stem cell activation

Satellite cells are crucial for growth and regeneration of skeletal muscle. Here the authors show that in response to muscle injury, macrophages secrete Adamts1, which induces satellite cell activation by modulating Notch1 signaling.

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Auteurs principaux: Hongqing Du, Chung-Hsuan Shih, Michael N. Wosczyna, Alisa A. Mueller, Joonseok Cho, Abhishek Aggarwal, Thomas A. Rando, Brian J. Feldman
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/b985b4346d2b4425bb7a38b75908eb78
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