Sirtuin 3 is essential for host defense against Mycobacterium abscessus infection through regulation of mitochondrial homeostasis

Sirtuin 3 is essential for host defense against Mycobacterium abscessus infection through regulation of mitochondrial homeostasis

The global incidence of Mycobacterium abscessus (Mabc), a rapidly growing nontuberculous mycobacterial strain that causes treatment-refractory pulmonary diseases, is increasing. Despite this, the host factors that allow for protection against infection are largely unknown. In this study, we found th...

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Auteurs principaux: Young Jae Kim, Sang-Hee Lee, Sang Min Jeon, Prashanta Silwal, Ju-Young Seo, Bui Thi Bich Hanh, June-Woo Park, Jake Whang, Min Joung Lee, Jun Young Heo, Soon Ha Kim, Jin-Man Kim, Gyu Yong Song, Jichan Jang, Eun-Kyeong Jo
Format: article
Langue:EN
Publié: Taylor & Francis Group 2020
Sujets:
mycobacterium abscessus
sirtuin 3
mitochondrial reactive oxygen species
resveratrol
host-directed therapy
Infectious and parasitic diseases
RC109-216
Accès en ligne:https://doaj.org/article/b98d4c77587d4a2b9f8a6da145888eb7
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https://doaj.org/article/b98d4c77587d4a2b9f8a6da145888eb7

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