Limited antibody specificity compromises epitranscriptomic analyses

A controversial discussion on the occurrence of the RNA modification m1A in mRNA takes a new turn, as an antibody with a central role in modification mapping was shown to also bind mRNA cap structures.

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Detalles Bibliográficos
Autores principales:	Mark Helm, Frank Lyko, Yuri Motorin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b98f534df82c4c40aeb2c82e40ecf7d9
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spelling	oai:doaj.org-article:b98f534df82c4c40aeb2c82e40ecf7d92021-12-02T14:40:18ZLimited antibody specificity compromises epitranscriptomic analyses10.1038/s41467-019-13684-32041-1723https://doaj.org/article/b98f534df82c4c40aeb2c82e40ecf7d92019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13684-3https://doaj.org/toc/2041-1723A controversial discussion on the occurrence of the RNA modification m1A in mRNA takes a new turn, as an antibody with a central role in modification mapping was shown to also bind mRNA cap structures.Mark HelmFrank LykoYuri MotorinNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-3 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mark Helm Frank Lyko Yuri Motorin Limited antibody specificity compromises epitranscriptomic analyses
description	A controversial discussion on the occurrence of the RNA modification m1A in mRNA takes a new turn, as an antibody with a central role in modification mapping was shown to also bind mRNA cap structures.
format	article
author	Mark Helm Frank Lyko Yuri Motorin
author_facet	Mark Helm Frank Lyko Yuri Motorin
author_sort	Mark Helm
title	Limited antibody specificity compromises epitranscriptomic analyses
title_short	Limited antibody specificity compromises epitranscriptomic analyses
title_full	Limited antibody specificity compromises epitranscriptomic analyses
title_fullStr	Limited antibody specificity compromises epitranscriptomic analyses
title_full_unstemmed	Limited antibody specificity compromises epitranscriptomic analyses
title_sort	limited antibody specificity compromises epitranscriptomic analyses
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/b98f534df82c4c40aeb2c82e40ecf7d9
work_keys_str_mv	AT markhelm limitedantibodyspecificitycompromisesepitranscriptomicanalyses AT franklyko limitedantibodyspecificitycompromisesepitranscriptomicanalyses AT yurimotorin limitedantibodyspecificitycompromisesepitranscriptomicanalyses
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Limited antibody specificity compromises epitranscriptomic analyses

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