Type I-F CRISPR-Cas resistance against virulent phages results in abortive infection and provides population-level immunity

Bacteria use CRISPR-Cas systems to protect themselves against viral infections. Here, Watson et al. show that a type I CRISPR-Cas system can induce abortive viral infection, where infected cells do not survive but viral propagation is decreased, thus protecting the bacterial population.

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Autores principales:	Bridget N. J. Watson, Reuben B. Vercoe, George P. C. Salmond, Edze R. Westra, Raymond H. J Staals, Peter C. Fineran
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b996789f39844bb4b36543b9bbb48b95
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spelling	oai:doaj.org-article:b996789f39844bb4b36543b9bbb48b952021-12-02T15:35:29ZType I-F CRISPR-Cas resistance against virulent phages results in abortive infection and provides population-level immunity10.1038/s41467-019-13445-22041-1723https://doaj.org/article/b996789f39844bb4b36543b9bbb48b952019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13445-2https://doaj.org/toc/2041-1723Bacteria use CRISPR-Cas systems to protect themselves against viral infections. Here, Watson et al. show that a type I CRISPR-Cas system can induce abortive viral infection, where infected cells do not survive but viral propagation is decreased, thus protecting the bacterial population.Bridget N. J. WatsonReuben B. VercoeGeorge P. C. SalmondEdze R. WestraRaymond H. J StaalsPeter C. FineranNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Bridget N. J. Watson Reuben B. Vercoe George P. C. Salmond Edze R. Westra Raymond H. J Staals Peter C. Fineran Type I-F CRISPR-Cas resistance against virulent phages results in abortive infection and provides population-level immunity
description	Bacteria use CRISPR-Cas systems to protect themselves against viral infections. Here, Watson et al. show that a type I CRISPR-Cas system can induce abortive viral infection, where infected cells do not survive but viral propagation is decreased, thus protecting the bacterial population.
format	article
author	Bridget N. J. Watson Reuben B. Vercoe George P. C. Salmond Edze R. Westra Raymond H. J Staals Peter C. Fineran
author_facet	Bridget N. J. Watson Reuben B. Vercoe George P. C. Salmond Edze R. Westra Raymond H. J Staals Peter C. Fineran
author_sort	Bridget N. J. Watson
title	Type I-F CRISPR-Cas resistance against virulent phages results in abortive infection and provides population-level immunity
title_short	Type I-F CRISPR-Cas resistance against virulent phages results in abortive infection and provides population-level immunity
title_full	Type I-F CRISPR-Cas resistance against virulent phages results in abortive infection and provides population-level immunity
title_fullStr	Type I-F CRISPR-Cas resistance against virulent phages results in abortive infection and provides population-level immunity
title_full_unstemmed	Type I-F CRISPR-Cas resistance against virulent phages results in abortive infection and provides population-level immunity
title_sort	type i-f crispr-cas resistance against virulent phages results in abortive infection and provides population-level immunity
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/b996789f39844bb4b36543b9bbb48b95
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Type I-F CRISPR-Cas resistance against virulent phages results in abortive infection and provides population-level immunity

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