Post-exposure immunotherapy for two ebolaviruses and Marburg virus in nonhuman primates

Post-exposure immunotherapy for two ebolaviruses and Marburg virus in nonhuman primates

Current experimental monoclonal antibodies (mAbs) for Ebola virus (EBOV) post-exposure immunotherapy are ineffective against Sudan (SUDV) or Marburg virus (MARV). Here, authors develop cocktails of mAbs that protect nonhuman primates against EBOV, SUDV, and MARV infection when given four days post i...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Jennifer M. Brannan, Shihua He, Katie A. Howell, Laura I. Prugar, Wenjun Zhu, Hong Vu, Sergey Shulenin, Shweta Kailasan, Henna Raina, Gary Wong, Md Niaz Rahim, Logan Banadyga, Kevin Tierney, Xuelian Zhao, Yuxing Li, Frederick W. Holtsberg, John M. Dye, Xiangguo Qiu, M. Javad Aman
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/b99aa7a0e5ce4018ab41eac4e31287f3
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:b99aa7a0e5ce4018ab41eac4e31287f3
record_format dspace
spelling oai:doaj.org-article:b99aa7a0e5ce4018ab41eac4e31287f32021-12-02T14:38:37ZPost-exposure immunotherapy for two ebolaviruses and Marburg virus in nonhuman primates10.1038/s41467-018-08040-w2041-1723https://doaj.org/article/b99aa7a0e5ce4018ab41eac4e31287f32019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-08040-whttps://doaj.org/toc/2041-1723Current experimental monoclonal antibodies (mAbs) for Ebola virus (EBOV) post-exposure immunotherapy are ineffective against Sudan (SUDV) or Marburg virus (MARV). Here, authors develop cocktails of mAbs that protect nonhuman primates against EBOV, SUDV, and MARV infection when given four days post infection.Jennifer M. BrannanShihua HeKatie A. HowellLaura I. PrugarWenjun ZhuHong VuSergey ShuleninShweta KailasanHenna RainaGary WongMd Niaz RahimLogan BanadygaKevin TierneyXuelian ZhaoYuxing LiFrederick W. HoltsbergJohn M. DyeXiangguo QiuM. Javad AmanNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jennifer M. Brannan
Shihua He
Katie A. Howell
Laura I. Prugar
Wenjun Zhu
Hong Vu
Sergey Shulenin
Shweta Kailasan
Henna Raina
Gary Wong
Md Niaz Rahim
Logan Banadyga
Kevin Tierney
Xuelian Zhao
Yuxing Li
Frederick W. Holtsberg
John M. Dye
Xiangguo Qiu
M. Javad Aman
Post-exposure immunotherapy for two ebolaviruses and Marburg virus in nonhuman primates
description Current experimental monoclonal antibodies (mAbs) for Ebola virus (EBOV) post-exposure immunotherapy are ineffective against Sudan (SUDV) or Marburg virus (MARV). Here, authors develop cocktails of mAbs that protect nonhuman primates against EBOV, SUDV, and MARV infection when given four days post infection.
format article
author Jennifer M. Brannan
Shihua He
Katie A. Howell
Laura I. Prugar
Wenjun Zhu
Hong Vu
Sergey Shulenin
Shweta Kailasan
Henna Raina
Gary Wong
Md Niaz Rahim
Logan Banadyga
Kevin Tierney
Xuelian Zhao
Yuxing Li
Frederick W. Holtsberg
John M. Dye
Xiangguo Qiu
M. Javad Aman
author_facet Jennifer M. Brannan
Shihua He
Katie A. Howell
Laura I. Prugar
Wenjun Zhu
Hong Vu
Sergey Shulenin
Shweta Kailasan
Henna Raina
Gary Wong
Md Niaz Rahim
Logan Banadyga
Kevin Tierney
Xuelian Zhao
Yuxing Li
Frederick W. Holtsberg
John M. Dye
Xiangguo Qiu
M. Javad Aman
author_sort Jennifer M. Brannan
title Post-exposure immunotherapy for two ebolaviruses and Marburg virus in nonhuman primates
title_short Post-exposure immunotherapy for two ebolaviruses and Marburg virus in nonhuman primates
title_full Post-exposure immunotherapy for two ebolaviruses and Marburg virus in nonhuman primates
title_fullStr Post-exposure immunotherapy for two ebolaviruses and Marburg virus in nonhuman primates
title_full_unstemmed Post-exposure immunotherapy for two ebolaviruses and Marburg virus in nonhuman primates
title_sort post-exposure immunotherapy for two ebolaviruses and marburg virus in nonhuman primates
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/b99aa7a0e5ce4018ab41eac4e31287f3
work_keys_str_mv AT jennifermbrannan postexposureimmunotherapyfortwoebolavirusesandmarburgvirusinnonhumanprimates
AT shihuahe postexposureimmunotherapyfortwoebolavirusesandmarburgvirusinnonhumanprimates
AT katieahowell postexposureimmunotherapyfortwoebolavirusesandmarburgvirusinnonhumanprimates
AT lauraiprugar postexposureimmunotherapyfortwoebolavirusesandmarburgvirusinnonhumanprimates
AT wenjunzhu postexposureimmunotherapyfortwoebolavirusesandmarburgvirusinnonhumanprimates
AT hongvu postexposureimmunotherapyfortwoebolavirusesandmarburgvirusinnonhumanprimates
AT sergeyshulenin postexposureimmunotherapyfortwoebolavirusesandmarburgvirusinnonhumanprimates
AT shwetakailasan postexposureimmunotherapyfortwoebolavirusesandmarburgvirusinnonhumanprimates
AT hennaraina postexposureimmunotherapyfortwoebolavirusesandmarburgvirusinnonhumanprimates
AT garywong postexposureimmunotherapyfortwoebolavirusesandmarburgvirusinnonhumanprimates
AT mdniazrahim postexposureimmunotherapyfortwoebolavirusesandmarburgvirusinnonhumanprimates
AT loganbanadyga postexposureimmunotherapyfortwoebolavirusesandmarburgvirusinnonhumanprimates
AT kevintierney postexposureimmunotherapyfortwoebolavirusesandmarburgvirusinnonhumanprimates
AT xuelianzhao postexposureimmunotherapyfortwoebolavirusesandmarburgvirusinnonhumanprimates
AT yuxingli postexposureimmunotherapyfortwoebolavirusesandmarburgvirusinnonhumanprimates
AT frederickwholtsberg postexposureimmunotherapyfortwoebolavirusesandmarburgvirusinnonhumanprimates
AT johnmdye postexposureimmunotherapyfortwoebolavirusesandmarburgvirusinnonhumanprimates
AT xiangguoqiu postexposureimmunotherapyfortwoebolavirusesandmarburgvirusinnonhumanprimates
AT mjavadaman postexposureimmunotherapyfortwoebolavirusesandmarburgvirusinnonhumanprimates
_version_ 1718390975006507008

Ejemplares similares