Structural insights into an atypical secretory pathway kinase crucial for Toxoplasma gondii invasion

Structural insights into an atypical secretory pathway kinase crucial for Toxoplasma gondii invasion

Host cell invasion by Toxoplasma gondii depends on the heavily phosphorylated RON complex, but the relevance and regulation of these modifications are not understood. Here, the authors identify the kinase RON13 as a key virulence factor, determine its structure and show that it phosphorylates the RO...

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Autores principales: Gaëlle Lentini, Rouaa Ben Chaabene, Oscar Vadas, Chandra Ramakrishnan, Budhaditya Mukherjee, Ved Mehta, Matteo Lunghi, Jonas Grossmann, Bohumil Maco, Rémy Visentin, Adrian B. Hehl, Volodymyr M. Korkhov, Dominique Soldati-Favre
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Science
Q
Acceso en línea:https://doaj.org/article/b99ddeb7c5ca4acfb20ea9d41fb9e96c
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