Circulating syndecan-1 is reduced in pregnancies with poor fetal growth and its secretion regulated by matrix metalloproteinases and the mitochondria

Circulating syndecan-1 is reduced in pregnancies with poor fetal growth and its secretion regulated by matrix metalloproteinases and the mitochondria

Abstract Fetal growth restriction is a leading cause of stillbirth that often remains undetected during pregnancy. Identifying novel biomarkers may improve detection of pregnancies at risk. This study aimed to assess syndecan-1 as a biomarker for small for gestational age (SGA) or fetal growth restr...

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Main Authors: Damanpreet Garcha, Susan P. Walker, Teresa M. MacDonald, Jon Hyett, Jessica Jellins, Jenny Myers, Sebastian E. Illanes, Jhy K. Nien, Manuel Schepeler, Emerson Keenan, Carole-Anne Whigham, Ping Cannon, Elizabeth Murray, Tuong-Vi Nguyen, Manju Kandel, Joshua Masci, Ciara Murphy, Tess Cruickshank, Natasha Pritchard, Natalie J. Hannan, Fiona Brownfoot, Alexandra Roddy Mitchell, Anna Middleton, Gabrielle Pell, Georgia P. Wong, Stephen Tong, Tu’uhevaha J. Kaitu’u-Lino
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/b9a4aa52db5d4a63b2d39175244dc8af
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https://doaj.org/article/b9a4aa52db5d4a63b2d39175244dc8af

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