Single-cell RNA-seq enables comprehensive tumour and immune cell profiling in primary breast cancer

Single-cell RNA-seq enables comprehensive tumour and immune cell profiling in primary breast cancer

Genetic heterogeneity in breast cancer has been demonstrated at a single-cell resolution with high levels of genome coverage. Here, the authors perform transcriptome analysis of 515 single cells from 11 patients and define core gene expression signatures for subtype-specific single breast cancer cel...

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Bibliographic Details
Main Authors: Woosung Chung, Hye Hyeon Eum, Hae-Ock Lee, Kyung-Min Lee, Han-Byoel Lee, Kyu-Tae Kim, Han Suk Ryu, Sangmin Kim, Jeong Eon Lee, Yeon Hee Park, Zhengyan Kan, Wonshik Han, Woong-Yang Park
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Science
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Online Access:https://doaj.org/article/b9a81dca4e5b4202ba19ac7f9d8afdd3
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