RISK FACTORS OF COGNITIVE IMPAIRMENT IN PARKINSON’S DISEASE AND DISCIRCULATORY ENCEPHALOPATHY

The aim of the study was to examine the state of cognitive functions in patients with Parkinson's disease combined with the dyscirculatory encephalopathy and identify their risk factors for cognitive impairment. The results of the study showed that the frequency of cognitive impairment in patie...

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Autores principales:	S. B. Sayutina, V. V. Shprakh, N. Y. Rozhkova
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2017
Materias:	parkinson's disease discirculatory encephalopathy cognitive impairment risk factors Science Q
Acceso en línea:	https://doaj.org/article/b9b02aad86dc4309a7aea001333cb2bb
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spelling	oai:doaj.org-article:b9b02aad86dc4309a7aea001333cb2bb2021-11-23T06:14:37ZRISK FACTORS OF COGNITIVE IMPAIRMENT IN PARKINSON’S DISEASE AND DISCIRCULATORY ENCEPHALOPATHY2541-94202587-959610.12737/article_59a614f9da7517.36264813https://doaj.org/article/b9b02aad86dc4309a7aea001333cb2bb2017-04-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/616https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The aim of the study was to examine the state of cognitive functions in patients with Parkinson's disease combined with the dyscirculatory encephalopathy and identify their risk factors for cognitive impairment. The results of the study showed that the frequency of cognitive impairment in patients with Parkinson's disease combined with the dyscirculatory encephalopathy was 90.3 %, Parkinson's disease without brain vascular disease - 28.6 %. Patients with concomitant cerebrovascular disease had more severe frontal deficit (mean score on the FAB in the main group -14.86 ± 2.18, in the control -16.93 ± 2.21; p < 0.0001), which manifested itself in the form of difficulty when performing tests for dynamic movements, simple and complicated reactions of choice, had the worst performance of speech and general mental activity, attention. In order to assess the relationship of certain clinical, social and biological factors with indicators of cognitive functions we conducted Spearman rank correlation analysis. Risk factors for the development of cognitive impairment of Parkinson's disease combined with vascular encephalopathy were age of patients, severity of motor impairment, duration and severity of hypertension, coronary heart disease, and the presence of acute cardiovascular events in history.S. B. SayutinaV. V. ShprakhN. Y. RozhkovaScientific Сentre for Family Health and Human Reproduction Problemsarticleparkinson's diseasediscirculatory encephalopathycognitive impairmentrisk factorsScienceQRUActa Biomedica Scientifica, Vol 2, Iss 2, Pp 45-47 (2017)
institution	DOAJ
collection	DOAJ
language	RU
topic	parkinson's disease discirculatory encephalopathy cognitive impairment risk factors Science Q
spellingShingle	parkinson's disease discirculatory encephalopathy cognitive impairment risk factors Science Q S. B. Sayutina V. V. Shprakh N. Y. Rozhkova RISK FACTORS OF COGNITIVE IMPAIRMENT IN PARKINSON’S DISEASE AND DISCIRCULATORY ENCEPHALOPATHY
description	The aim of the study was to examine the state of cognitive functions in patients with Parkinson's disease combined with the dyscirculatory encephalopathy and identify their risk factors for cognitive impairment. The results of the study showed that the frequency of cognitive impairment in patients with Parkinson's disease combined with the dyscirculatory encephalopathy was 90.3 %, Parkinson's disease without brain vascular disease - 28.6 %. Patients with concomitant cerebrovascular disease had more severe frontal deficit (mean score on the FAB in the main group -14.86 ± 2.18, in the control -16.93 ± 2.21; p < 0.0001), which manifested itself in the form of difficulty when performing tests for dynamic movements, simple and complicated reactions of choice, had the worst performance of speech and general mental activity, attention. In order to assess the relationship of certain clinical, social and biological factors with indicators of cognitive functions we conducted Spearman rank correlation analysis. Risk factors for the development of cognitive impairment of Parkinson's disease combined with vascular encephalopathy were age of patients, severity of motor impairment, duration and severity of hypertension, coronary heart disease, and the presence of acute cardiovascular events in history.
format	article
author	S. B. Sayutina V. V. Shprakh N. Y. Rozhkova
author_facet	S. B. Sayutina V. V. Shprakh N. Y. Rozhkova
author_sort	S. B. Sayutina
title	RISK FACTORS OF COGNITIVE IMPAIRMENT IN PARKINSON’S DISEASE AND DISCIRCULATORY ENCEPHALOPATHY
title_short	RISK FACTORS OF COGNITIVE IMPAIRMENT IN PARKINSON’S DISEASE AND DISCIRCULATORY ENCEPHALOPATHY
title_full	RISK FACTORS OF COGNITIVE IMPAIRMENT IN PARKINSON’S DISEASE AND DISCIRCULATORY ENCEPHALOPATHY
title_fullStr	RISK FACTORS OF COGNITIVE IMPAIRMENT IN PARKINSON’S DISEASE AND DISCIRCULATORY ENCEPHALOPATHY
title_full_unstemmed	RISK FACTORS OF COGNITIVE IMPAIRMENT IN PARKINSON’S DISEASE AND DISCIRCULATORY ENCEPHALOPATHY
title_sort	risk factors of cognitive impairment in parkinson’s disease and discirculatory encephalopathy
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2017
url	https://doaj.org/article/b9b02aad86dc4309a7aea001333cb2bb
work_keys_str_mv	AT sbsayutina riskfactorsofcognitiveimpairmentinparkinsonsdiseaseanddiscirculatoryencephalopathy AT vvshprakh riskfactorsofcognitiveimpairmentinparkinsonsdiseaseanddiscirculatoryencephalopathy AT nyrozhkova riskfactorsofcognitiveimpairmentinparkinsonsdiseaseanddiscirculatoryencephalopathy
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RISK FACTORS OF COGNITIVE IMPAIRMENT IN PARKINSON’S DISEASE AND DISCIRCULATORY ENCEPHALOPATHY

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